Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia in the elderly. The instances of AD are rapidly increasing and there is no cure currently available for this devastating disease. Current therapies for the disease allow AD patients to delay or mitigate the symptoms in order to improve their quality of life; however, these therapies do not halt disease progression.
","abstract_html":"<p>Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia in the elderly. The instances of AD are rapidly increasing and there is no cure currently available for this devastating disease. Current therapies for the disease allow AD patients to delay or mitigate the symptoms in order to improve their quality of life; however, these therapies do not halt disease progression.</p>","abstract_has_math":false,"creators":["Soto-Ortega, Deborah"],"institution":null,"degree_name":"Ph.D.","degree_level":"Campus Access Dissertation","degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Melissa A Moss"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2010,"date_issued":"2010-01-01T08:00:00Z","date_published":"2010-01-01T08:00:00Z","updated_at":"2026-07-24T04:36:56Z","subjects":["Biomedical","Electrical and Computer Engineering","Engineering","Alzheimer's Disease","Amyloid-Beta","Inhibition"],"languages":[],"rights":["© 2010, Deborah Soto-Ortega"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarcommons.sc.edu/etd/534","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Melissa A Moss"]},{"key":"dc:creator","label":"Author","values":["Soto-Ortega, Deborah"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Campus Access Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biomedical","Electrical and Computer Engineering","Engineering","Alzheimer's Disease","Amyloid-Beta","Inhibition"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["© 2010, Deborah Soto-Ortega"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarcommons.sc.edu/etd/534"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia in the elderly. The instances of AD are rapidly increasing and there is no cure currently available for this devastating disease. Current therapies for the disease allow AD patients to delay or mitigate the symptoms in order to improve their quality of life; however, these therapies do not halt disease progression.
"]},{"key":"dc:title","label":"Title","values":["Study of Structural and Physical Properties of Small Molecule and Nanoparticle Inhibitors of Amyloid-B Protein Fibril Formation In Alzheimer'S Disease"]}]}],"canonical_facts":{"dc:contributor":["Melissa A Moss"],"dc:creator":["Soto-Ortega, Deborah"],"dc:description.abstract":["Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia in the elderly. The instances of AD are rapidly increasing and there is no cure currently available for this devastating disease. Current therapies for the disease allow AD patients to delay or mitigate the symptoms in order to improve their quality of life; however, these therapies do not halt disease progression.
"],"dc:identifier":["https://scholarcommons.sc.edu/etd/534"],"dc:rights":["© 2010, Deborah Soto-Ortega"],"dc:subject":["Biomedical","Electrical and Computer Engineering","Engineering","Alzheimer's Disease","Amyloid-Beta","Inhibition"],"dc:title":["Study of Structural and Physical Properties of Small Molecule and Nanoparticle Inhibitors of Amyloid-B Protein Fibril Formation In Alzheimer'S Disease"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_level":["Campus Access Dissertation"],"thesis:degree_name":["Ph.D."]},"updated_at":"2026-07-24T04:36:56Z"}