{"id":{"repo_id":"soton","oai_identifier":"oai:eprints.soton.ac.uk:161439"},"canonical_url":"https://search.dev.ndltd.org/etd/soton/oai:eprints.soton.ac.uk:161439","repository":{"repo_id":"soton","name":"University of Southampton","base_url":"https://eprints.soton.ac.uk/cgi/oai2"},"display":{"title":"Comparison of different methods of categorization for physical activity on coronary heart disease risk factors","abstract":"Objective: There is a general agreement that physical activity (PA) has a beneficial effect<br/>on health and those who are more active have a reduced risk of developing many chronic<br/>diseases, such as coronary heart disease (CHD). However, the amount, type and intensity<br/>of PA deemed to be sufficient to achieve good health remains unclear. Different methods<br/>have been used to categorise activity behaviour, but the level of agreement, consistency<br/>and coherence between methods and how this might influence their relationship with CHD<br/>risk factors and estimated CHD (eCHD) risk are poorly understood. This uncertainty is<br/>reflected in many different messages communicated to the public as to how active they<br/>should be to prevent chronic diseases. The primary objective of this thesis was to<br/>determine whether the methods used to categorise PA (as either inactive/active or level of<br/>PA) influence the extent to which PA is associated with CHD risk factors and eCHD risk.<br/><br/>Methods: This thesis was divided into two parts. The first part was to conduct a<br/>secondary analysis of data on activity and CHD risk factors (blood pressure and lipid<br/>profile) obtained from the 2004 UK National Diet and Nutrition Survey (NDNS) in 1658<br/>adults aged 19-64 years. Using the information obtained from the NDNS 7-day diary, it<br/>was possible to extend the original observations and to re-categorise individuals according<br/>to measures of PA in terms of number of days and minutes of at least moderate PA, total<br/>activity expressed as metabolic-equivalents (METs) and self-perception of PA. Each of<br/>these methods was then used to examine the proportion of the variance in CHD risk<br/>factors and the eCHD risk attributable to differences in PA using General Linear<br/>Modelling with adjustment for BMI, age and smoking. Partial eta squared a “proportion of<br/>variance due to physical activity plus error that is attributed to physical activity alone” was<br/>used. In the second part, the concurrent validity of measures of PA derived from the<br/>NDNS 7-day diary, using different systems for coding and classifying of different physical<br/>activities, was compared against those measures of PA obtained from the International<br/>Physical Activity Questionnaire (IPAQ) in a group of medical students (n = 26).<br/><br/>Results: Taken together, this thesis revealed: 1) poor agreement across different methods<br/>of categorisation of PA level, 2) no support to justify a curvilinear dose-response<br/>relationship between PA level and CHD risk factors and eCHD risk and that a linear<br/>model was sufficient, 3) the differences in CHD risk factors or eCHD risk that could be<br/>directly attributable to differences in PA in men was modest (generally &lt; 5%) although no<br/>associations evident in the women, 4) effect was most obviously demonstrable as<br/>improvements in lipid profile, no demonstrable effect on blood pressure, 5) a potential<br/>problem might arise when using one system and applying its results to different guidelines<br/>established by different systems.<br/><br/>Conclusion: These findings support the view that being physically active is associated<br/>with markers of better health and lower CHD risk; a small but consistent effect that was<br/>the same irrespective of which method of categorizing PA was used and even after<br/>adjustment for differences in age, BMI and smoking. The effects were most evident in<br/>men and largely attributable to improvements in lipid metabolism.","abstract_html":"Objective: There is a general agreement that physical activity (PA) has a beneficial effect&lt;br/&gt;on health and those who are more active have a reduced risk of developing many chronic&lt;br/&gt;diseases, such as coronary heart disease (CHD). However, the amount, type and intensity&lt;br/&gt;of PA deemed to be sufficient to achieve good health remains unclear. Different methods&lt;br/&gt;have been used to categorise activity behaviour, but the level of agreement, consistency&lt;br/&gt;and coherence between methods and how this might influence their relationship with CHD&lt;br/&gt;risk factors and estimated CHD (eCHD) risk are poorly understood. This uncertainty is&lt;br/&gt;reflected in many different messages communicated to the public as to how active they&lt;br/&gt;should be to prevent chronic diseases. The primary objective of this thesis was to&lt;br/&gt;determine whether the methods used to categorise PA (as either inactive/active or level of&lt;br/&gt;PA) influence the extent to which PA is associated with CHD risk factors and eCHD risk.&lt;br/&gt;&lt;br/&gt;Methods: This thesis was divided into two parts. The first part was to conduct a&lt;br/&gt;secondary analysis of data on activity and CHD risk factors (blood pressure and lipid&lt;br/&gt;profile) obtained from the 2004 UK National Diet and Nutrition Survey (NDNS) in 1658&lt;br/&gt;adults aged 19-64 years. Using the information obtained from the NDNS 7-day diary, it&lt;br/&gt;was possible to extend the original observations and to re-categorise individuals according&lt;br/&gt;to measures of PA in terms of number of days and minutes of at least moderate PA, total&lt;br/&gt;activity expressed as metabolic-equivalents (METs) and self-perception of PA. Each of&lt;br/&gt;these methods was then used to examine the proportion of the variance in CHD risk&lt;br/&gt;factors and the eCHD risk attributable to differences in PA using General Linear&lt;br/&gt;Modelling with adjustment for BMI, age and smoking. Partial eta squared a “proportion of&lt;br/&gt;variance due to physical activity plus error that is attributed to physical activity alone” was&lt;br/&gt;used. In the second part, the concurrent validity of measures of PA derived from the&lt;br/&gt;NDNS 7-day diary, using different systems for coding and classifying of different physical&lt;br/&gt;activities, was compared against those measures of PA obtained from the International&lt;br/&gt;Physical Activity Questionnaire (IPAQ) in a group of medical students (n = 26).&lt;br/&gt;&lt;br/&gt;Results: Taken together, this thesis revealed: 1) poor agreement across different methods&lt;br/&gt;of categorisation of PA level, 2) no support to justify a curvilinear dose-response&lt;br/&gt;relationship between PA level and CHD risk factors and eCHD risk and that a linear&lt;br/&gt;model was sufficient, 3) the differences in CHD risk factors or eCHD risk that could be&lt;br/&gt;directly attributable to differences in PA in men was modest (generally &amp;lt; 5%) although no&lt;br/&gt;associations evident in the women, 4) effect was most obviously demonstrable as&lt;br/&gt;improvements in lipid profile, no demonstrable effect on blood pressure, 5) a potential&lt;br/&gt;problem might arise when using one system and applying its results to different guidelines&lt;br/&gt;established by different systems.&lt;br/&gt;&lt;br/&gt;Conclusion: These findings support the view that being physically active is associated&lt;br/&gt;with markers of better health and lower CHD risk; a small but consistent effect that was&lt;br/&gt;the same irrespective of which method of categorizing PA was used and even after&lt;br/&gt;adjustment for differences in age, BMI and smoking. The effects were most evident in&lt;br/&gt;men and largely attributable to improvements in lipid metabolism.","abstract_has_math":false,"creators":["Al-Haifi, Ahmad"],"institution":"University of Southampton","degree_name":"Ph.D.","degree_level":"doctoral","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Elia, Marinos","Wootton, Steve"],"committee_chairs":[],"committee_members":[],"year":2008,"date_issued":"2008-09","date_published":"2008-09","updated_at":"2026-07-24T04:36:17Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Elia, Marinos","Wootton, Steve"]},{"key":"dc:creator","label":"Author","values":["Al-Haifi, Ahmad"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2008-09-25"]},{"key":"dc:date.issued","label":"Date","values":["2008-09"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Dev Origins of Health & Disease (pre 2011 reorg)","School of Medicine"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Southampton"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://eprints.soton.ac.uk/161439/"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["Ph.D."]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://eprints.soton.ac.uk/161439/1/Ahmad-_Final_thesis.pdf"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Objective: There is a general agreement that physical activity (PA) has a beneficial effect<br/>on health and those who are more active have a reduced risk of developing many chronic<br/>diseases, such as coronary heart disease (CHD). However, the amount, type and intensity<br/>of PA deemed to be sufficient to achieve good health remains unclear. Different methods<br/>have been used to categorise activity behaviour, but the level of agreement, consistency<br/>and coherence between methods and how this might influence their relationship with CHD<br/>risk factors and estimated CHD (eCHD) risk are poorly understood. This uncertainty is<br/>reflected in many different messages communicated to the public as to how active they<br/>should be to prevent chronic diseases. The primary objective of this thesis was to<br/>determine whether the methods used to categorise PA (as either inactive/active or level of<br/>PA) influence the extent to which PA is associated with CHD risk factors and eCHD risk.<br/><br/>Methods: This thesis was divided into two parts. The first part was to conduct a<br/>secondary analysis of data on activity and CHD risk factors (blood pressure and lipid<br/>profile) obtained from the 2004 UK National Diet and Nutrition Survey (NDNS) in 1658<br/>adults aged 19-64 years. Using the information obtained from the NDNS 7-day diary, it<br/>was possible to extend the original observations and to re-categorise individuals according<br/>to measures of PA in terms of number of days and minutes of at least moderate PA, total<br/>activity expressed as metabolic-equivalents (METs) and self-perception of PA. Each of<br/>these methods was then used to examine the proportion of the variance in CHD risk<br/>factors and the eCHD risk attributable to differences in PA using General Linear<br/>Modelling with adjustment for BMI, age and smoking. Partial eta squared a “proportion of<br/>variance due to physical activity plus error that is attributed to physical activity alone” was<br/>used. In the second part, the concurrent validity of measures of PA derived from the<br/>NDNS 7-day diary, using different systems for coding and classifying of different physical<br/>activities, was compared against those measures of PA obtained from the International<br/>Physical Activity Questionnaire (IPAQ) in a group of medical students (n = 26).<br/><br/>Results: Taken together, this thesis revealed: 1) poor agreement across different methods<br/>of categorisation of PA level, 2) no support to justify a curvilinear dose-response<br/>relationship between PA level and CHD risk factors and eCHD risk and that a linear<br/>model was sufficient, 3) the differences in CHD risk factors or eCHD risk that could be<br/>directly attributable to differences in PA in men was modest (generally &lt; 5%) although no<br/>associations evident in the women, 4) effect was most obviously demonstrable as<br/>improvements in lipid profile, no demonstrable effect on blood pressure, 5) a potential<br/>problem might arise when using one system and applying its results to different guidelines<br/>established by different systems.<br/><br/>Conclusion: These findings support the view that being physically active is associated<br/>with markers of better health and lower CHD risk; a small but consistent effect that was<br/>the same irrespective of which method of categorizing PA was used and even after<br/>adjustment for differences in age, BMI and smoking. The effects were most evident in<br/>men and largely attributable to improvements in lipid metabolism."]},{"key":"dc:format","label":"Dc Format","values":["text"]},{"key":"dc:title","label":"Title","values":["Comparison of different methods of categorization for physical activity on coronary heart disease risk factors"]}]}],"canonical_facts":{"dc:contributor.advisor":["Elia, Marinos","Wootton, Steve"],"dc:creator":["Al-Haifi, Ahmad"],"dc:date":["2008-09-25"],"dc:date.issued":["2008-09"],"dc:description.abstract":["Objective: There is a general agreement that physical activity (PA) has a beneficial effect<br/>on health and those who are more active have a reduced risk of developing many chronic<br/>diseases, such as coronary heart disease (CHD). However, the amount, type and intensity<br/>of PA deemed to be sufficient to achieve good health remains unclear. Different methods<br/>have been used to categorise activity behaviour, but the level of agreement, consistency<br/>and coherence between methods and how this might influence their relationship with CHD<br/>risk factors and estimated CHD (eCHD) risk are poorly understood. This uncertainty is<br/>reflected in many different messages communicated to the public as to how active they<br/>should be to prevent chronic diseases. The primary objective of this thesis was to<br/>determine whether the methods used to categorise PA (as either inactive/active or level of<br/>PA) influence the extent to which PA is associated with CHD risk factors and eCHD risk.<br/><br/>Methods: This thesis was divided into two parts. The first part was to conduct a<br/>secondary analysis of data on activity and CHD risk factors (blood pressure and lipid<br/>profile) obtained from the 2004 UK National Diet and Nutrition Survey (NDNS) in 1658<br/>adults aged 19-64 years. Using the information obtained from the NDNS 7-day diary, it<br/>was possible to extend the original observations and to re-categorise individuals according<br/>to measures of PA in terms of number of days and minutes of at least moderate PA, total<br/>activity expressed as metabolic-equivalents (METs) and self-perception of PA. Each of<br/>these methods was then used to examine the proportion of the variance in CHD risk<br/>factors and the eCHD risk attributable to differences in PA using General Linear<br/>Modelling with adjustment for BMI, age and smoking. Partial eta squared a “proportion of<br/>variance due to physical activity plus error that is attributed to physical activity alone” was<br/>used. In the second part, the concurrent validity of measures of PA derived from the<br/>NDNS 7-day diary, using different systems for coding and classifying of different physical<br/>activities, was compared against those measures of PA obtained from the International<br/>Physical Activity Questionnaire (IPAQ) in a group of medical students (n = 26).<br/><br/>Results: Taken together, this thesis revealed: 1) poor agreement across different methods<br/>of categorisation of PA level, 2) no support to justify a curvilinear dose-response<br/>relationship between PA level and CHD risk factors and eCHD risk and that a linear<br/>model was sufficient, 3) the differences in CHD risk factors or eCHD risk that could be<br/>directly attributable to differences in PA in men was modest (generally &lt; 5%) although no<br/>associations evident in the women, 4) effect was most obviously demonstrable as<br/>improvements in lipid profile, no demonstrable effect on blood pressure, 5) a potential<br/>problem might arise when using one system and applying its results to different guidelines<br/>established by different systems.<br/><br/>Conclusion: These findings support the view that being physically active is associated<br/>with markers of better health and lower CHD risk; a small but consistent effect that was<br/>the same irrespective of which method of categorizing PA was used and even after<br/>adjustment for differences in age, BMI and smoking. The effects were most evident in<br/>men and largely attributable to improvements in lipid metabolism."],"dc:format":["text"],"dc:identifier.uri":["https://eprints.soton.ac.uk/161439/1/Ahmad-_Final_thesis.pdf"],"dc:publisher.department":["Dev Origins of Health & Disease (pre 2011 reorg)","School of Medicine"],"dc:publisher.institution":["University of Southampton"],"dc:relation.isreferencedby":["https://eprints.soton.ac.uk/161439/"],"dc:title":["Comparison of different methods of categorization for physical activity on coronary heart disease risk factors"],"dc:type":["Thesis"],"dc:type.qualificationlevel":["doctoral"],"dc:type.qualificationname":["Ph.D."]},"updated_at":"2026-07-24T04:36:17Z"}