{"id":{"repo_id":"sherbrooke","oai_identifier":"oai:usherbrooke.scholaris.ca:11143/21832"},"canonical_url":"https://search.dev.ndltd.org/etd/sherbrooke/oai:usherbrooke.scholaris.ca:11143/21832","repository":{"repo_id":"sherbrooke","name":"Université de Sherbrooke","base_url":"https://usherbrooke.scholaris.ca/server/oai/request"},"display":{"title":"Intervention en téléréadaptation et caractérisation de la dysautonomie cardiovasculaire dans la maladie de Parkinson","abstract":"Introduction: The prevalence of Parkinson's disease (PD), which primarily affects the elderly, is constantly increasing. PD causes non-motor symptoms, such as cardiovascular dysautonomia (CD). Still underdiagnosed in clinics, CD poses risks to patients' health. Physical activity could improve CD and practicing it via telerehabilitation (TR) could reach a larger population. The objectives are 1) to assess the feasibility, acceptability, and explore the potential effects of a TR program on CD; and 2) to characterize CD in PD through objective and self-reported symptom measurements. Methods: 30 individuals with PD were contacted, of whom 16 underwent an active orthostatic hypotension (OH) test to detect CD (OH and/or supine hypertension-SH). Characterization was further complemented by heart rate variability (HRV) testing, galvanic skin response (GSR) and self-reported symptom questionnaires. Participants who tested positive for CD were invited to participated in a 12week hybrid (supervised/unsupervised) TR program. Feasibility (recruitment, retention and adherence rates, and safety), acceptability (satisfaction questionnaire and semi-structured interviews) and potential effects (HRV, GSR, self-reported symptoms, 24-hour ambulatory blood pressure monitoring, 6-minute walk test (6MWT)) were evaluated. Results: CD was detected in 5 out of 16 screened participants. No significant differences were observed between the groups with (CD+) and without (CD-) dysautonomia, and no clear trends emerged. Exploratory analyses identified different profiles within the CD+ group, including a more pronounced CD for patients with SH. The TR program had a low recruitment rate (10%) but good retention (100%) and adherence (91%) rates for the 3 participants who completed it. The intervention did not present any adverse events and acceptability was good according to the participants' perspective. The potential effects showed no trend on DC, while 6MWT indicated an improvement of cardiovascular capacity. Conclusion: The active OH test appears to be useful in identifying CD in PD. Different profiles among patients with CD may be identified. Despite a low recruitment rate, the TR program seems appropriate and responsive to the needs individuals with CD in PD. However, it seems necessary to improve accessibility strategies to reach a larger portion of the population and thus demonstrate the potential effects of such a RT program.","abstract_html":"Introduction: The prevalence of Parkinson's disease (PD), which primarily affects the elderly, is constantly increasing. PD causes non-motor symptoms, such as cardiovascular dysautonomia (CD). Still underdiagnosed in clinics, CD poses risks to patients' health. Physical activity could improve CD and practicing it via telerehabilitation (TR) could reach a larger population. The objectives are 1) to assess the feasibility, acceptability, and explore the potential effects of a TR program on CD; and 2) to characterize CD in PD through objective and self-reported symptom measurements. Methods: 30 individuals with PD were contacted, of whom 16 underwent an active orthostatic hypotension (OH) test to detect CD (OH and/or supine hypertension-SH). Characterization was further complemented by heart rate variability (HRV) testing, galvanic skin response (GSR) and self-reported symptom questionnaires. Participants who tested positive for CD were invited to participated in a 12week hybrid (supervised/unsupervised) TR program. Feasibility (recruitment, retention and adherence rates, and safety), acceptability (satisfaction questionnaire and semi-structured interviews) and potential effects (HRV, GSR, self-reported symptoms, 24-hour ambulatory blood pressure monitoring, 6-minute walk test (6MWT)) were evaluated. Results: CD was detected in 5 out of 16 screened participants. No significant differences were observed between the groups with (CD+) and without (CD-) dysautonomia, and no clear trends emerged. Exploratory analyses identified different profiles within the CD+ group, including a more pronounced CD for patients with SH. The TR program had a low recruitment rate (10%) but good retention (100%) and adherence (91%) rates for the 3 participants who completed it. The intervention did not present any adverse events and acceptability was good according to the participants' perspective. The potential effects showed no trend on DC, while 6MWT indicated an improvement of cardiovascular capacity. Conclusion: The active OH test appears to be useful in identifying CD in PD. Different profiles among patients with CD may be identified. Despite a low recruitment rate, the TR program seems appropriate and responsive to the needs individuals with CD in PD. However, it seems necessary to improve accessibility strategies to reach a larger portion of the population and thus demonstrate the potential effects of such a RT program.","abstract_has_math":false,"creators":["Crépin, Léo"],"institution":"Université de Sherbrooke","degree_name":"M. Sc.","degree_level":"Maîtrise","degree_discipline":"Réadaptation","degree_department":null,"school":null,"contributors":[],"advisors":["Léonard, Guillaume","Pinheiro Carvalho, Livia"],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024","date_published":"2024","updated_at":"2026-07-27T21:07:59Z","subjects":["Maladie de Parkinson","Téléréadaptation","Dysautonomie","Cardiovasculaire","Parkinson’s disease","Telerehabilitation","Dysautonomia","Cardiovascular"],"languages":["fr","en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/11143/21832","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Léonard, Guillaume","Pinheiro Carvalho, Livia"]},{"key":"dc:creator","label":"Author","values":["Crépin, Léo"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2024-08-20T14:54:11Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2024-08-20T14:54:11Z"]},{"key":"dc:date.issued","label":"Date","values":["2024"]},{"key":"dc:publisher","label":"Institution","values":["Université de Sherbrooke"]},{"key":"dc:type","label":"Dc Type","values":["Mémoire de maîtrise"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Réadaptation"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Maîtrise"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M. Sc."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Faculté de médecine et des sciences de la santé"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Maladie de Parkinson","Téléréadaptation","Dysautonomie","Cardiovasculaire","Parkinson’s disease","Telerehabilitation","Dysautonomia","Cardiovascular"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["fr","en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/11143/21832"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Introduction: The prevalence of Parkinson's disease (PD), which primarily affects the elderly, is constantly increasing. PD causes non-motor symptoms, such as cardiovascular dysautonomia (CD). Still underdiagnosed in clinics, CD poses risks to patients' health. Physical activity could improve CD and practicing it via telerehabilitation (TR) could reach a larger population. The objectives are 1) to assess the feasibility, acceptability, and explore the potential effects of a TR program on CD; and 2) to characterize CD in PD through objective and self-reported symptom measurements. Methods: 30 individuals with PD were contacted, of whom 16 underwent an active orthostatic hypotension (OH) test to detect CD (OH and/or supine hypertension-SH). Characterization was further complemented by heart rate variability (HRV) testing, galvanic skin response (GSR) and self-reported symptom questionnaires. Participants who tested positive for CD were invited to participated in a 12week hybrid (supervised/unsupervised) TR program. Feasibility (recruitment, retention and adherence rates, and safety), acceptability (satisfaction questionnaire and semi-structured interviews) and potential effects (HRV, GSR, self-reported symptoms, 24-hour ambulatory blood pressure monitoring, 6-minute walk test (6MWT)) were evaluated. Results: CD was detected in 5 out of 16 screened participants. No significant differences were observed between the groups with (CD+) and without (CD-) dysautonomia, and no clear trends emerged. Exploratory analyses identified different profiles within the CD+ group, including a more pronounced CD for patients with SH. The TR program had a low recruitment rate (10%) but good retention (100%) and adherence (91%) rates for the 3 participants who completed it. The intervention did not present any adverse events and acceptability was good according to the participants' perspective. The potential effects showed no trend on DC, while 6MWT indicated an improvement of cardiovascular capacity. Conclusion: The active OH test appears to be useful in identifying CD in PD. Different profiles among patients with CD may be identified. Despite a low recruitment rate, the TR program seems appropriate and responsive to the needs individuals with CD in PD. However, it seems necessary to improve accessibility strategies to reach a larger portion of the population and thus demonstrate the potential effects of such a RT program.","Introduction : La prévalence de la maladie de Parkinson (MP), affectant principalement les personnes âgées, ne cesse d’augmenter. La MP entraine des symptômes non-moteurs, comme la dysautonomie cardiovasculaire (DC). Encore trop peu explorée sur le terrain, elle entraine des risques pour la santé des patients. L’activité physique pourrait améliorer la DC et la pratiquer via la téléréadaptation (TR) permettrait d’atteindre un plus grand nombre de personnes. Les objectifs de l’étude sont 1) d’évaluer la faisabilité, l’acceptabilité et d’explorer les effets potentiels d’un programme de TR sur la DC; et 2) de caractériser la DC dans la MP par des mesures objectives et auto-rapportées des symptômes. Méthodes : 30 personnes atteintes de la MP ont été contactées, parmi lesquels 16 ont réalisé un test actif d’hypotension orthostatique (HO) pour dépister la DC (HO et/ou hypertension couchée-HC). La caractérisation a été complétée avec un test de variabilité de fréquence cardiaque (VFC), de réponse galvanique cutanée (RGC) et des questionnaires de symptômes auto-rapportés. Les participants positifs à la DC ont été invités à participer à un programme hybride (supervisé/non-supervisé) de TR de 12 semaines. La faisabilité (taux de recrutement, rétention et adhésion et sécurité), l’acceptabilité (questionnaire de satisfaction et entretiens semi-dirigés) et les effets potentiels (VFC, RGC, symptômes auto-rapportés, monitoring ambulatoire de pression artérielle 24h, test de marche de 6 minutes-TDM6) ont été évalués. Résultats : Une DC a été détectée chez 5 des 16 participants évalués. Il n’y a pas de différence significative entre les groupes avec (DC+) et sans (DC-) dysautonomie et aucune tendance n’a été observée. Des analyses exploratoires ont permis d’identifier des profils au sein du groupe DC+, notamment avec une DC plus prononcée pour les patients avec HC. De son côté, l’intervention a un faible taux de recrutement (10%) mais de bons taux de rétention (100%) et d’adhésion (91%) pour les 3 participants l’ayant complétée. Aucun évènement indésirable n'est survenu et l’acceptabilité par les participants a été bonne. Les effets potentiels n’ont montré aucune tendance sur la DC, alors que le TDM6 indique une amélioration de la capacité cardiovasculaire. Conclusion : Le test actif d’HO semble permettre d’identifier la DC dans la MP. Différents profils chez les patients atteints de DC pourrait être identifiés. Malgré un faible taux de recrutement, le programme de TR semble adapté et bien répondre aux besoins des personnes atteintes DC dans la MP. Néanmoins, il parait impératif d'améliorer les stratégies d'accessibilité pour atteindre une plus grande portion de la population et ainsi démontrer les effets potentiels d’un tel programme de TR."]},{"key":"dc:title","label":"Title","values":["Intervention en téléréadaptation et caractérisation de la dysautonomie cardiovasculaire dans la maladie de Parkinson"]}]}],"canonical_facts":{"dc:contributor.advisor":["Léonard, Guillaume","Pinheiro Carvalho, Livia"],"dc:creator":["Crépin, Léo"],"dc:date.accessioned":["2024-08-20T14:54:11Z"],"dc:date.available":["2024-08-20T14:54:11Z"],"dc:date.issued":["2024"],"dc:description.abstract":["Introduction: The prevalence of Parkinson's disease (PD), which primarily affects the elderly, is constantly increasing. PD causes non-motor symptoms, such as cardiovascular dysautonomia (CD). Still underdiagnosed in clinics, CD poses risks to patients' health. Physical activity could improve CD and practicing it via telerehabilitation (TR) could reach a larger population. The objectives are 1) to assess the feasibility, acceptability, and explore the potential effects of a TR program on CD; and 2) to characterize CD in PD through objective and self-reported symptom measurements. Methods: 30 individuals with PD were contacted, of whom 16 underwent an active orthostatic hypotension (OH) test to detect CD (OH and/or supine hypertension-SH). Characterization was further complemented by heart rate variability (HRV) testing, galvanic skin response (GSR) and self-reported symptom questionnaires. Participants who tested positive for CD were invited to participated in a 12week hybrid (supervised/unsupervised) TR program. Feasibility (recruitment, retention and adherence rates, and safety), acceptability (satisfaction questionnaire and semi-structured interviews) and potential effects (HRV, GSR, self-reported symptoms, 24-hour ambulatory blood pressure monitoring, 6-minute walk test (6MWT)) were evaluated. Results: CD was detected in 5 out of 16 screened participants. No significant differences were observed between the groups with (CD+) and without (CD-) dysautonomia, and no clear trends emerged. Exploratory analyses identified different profiles within the CD+ group, including a more pronounced CD for patients with SH. The TR program had a low recruitment rate (10%) but good retention (100%) and adherence (91%) rates for the 3 participants who completed it. The intervention did not present any adverse events and acceptability was good according to the participants' perspective. The potential effects showed no trend on DC, while 6MWT indicated an improvement of cardiovascular capacity. Conclusion: The active OH test appears to be useful in identifying CD in PD. Different profiles among patients with CD may be identified. Despite a low recruitment rate, the TR program seems appropriate and responsive to the needs individuals with CD in PD. However, it seems necessary to improve accessibility strategies to reach a larger portion of the population and thus demonstrate the potential effects of such a RT program.","Introduction : La prévalence de la maladie de Parkinson (MP), affectant principalement les personnes âgées, ne cesse d’augmenter. La MP entraine des symptômes non-moteurs, comme la dysautonomie cardiovasculaire (DC). Encore trop peu explorée sur le terrain, elle entraine des risques pour la santé des patients. L’activité physique pourrait améliorer la DC et la pratiquer via la téléréadaptation (TR) permettrait d’atteindre un plus grand nombre de personnes. Les objectifs de l’étude sont 1) d’évaluer la faisabilité, l’acceptabilité et d’explorer les effets potentiels d’un programme de TR sur la DC; et 2) de caractériser la DC dans la MP par des mesures objectives et auto-rapportées des symptômes. Méthodes : 30 personnes atteintes de la MP ont été contactées, parmi lesquels 16 ont réalisé un test actif d’hypotension orthostatique (HO) pour dépister la DC (HO et/ou hypertension couchée-HC). La caractérisation a été complétée avec un test de variabilité de fréquence cardiaque (VFC), de réponse galvanique cutanée (RGC) et des questionnaires de symptômes auto-rapportés. Les participants positifs à la DC ont été invités à participer à un programme hybride (supervisé/non-supervisé) de TR de 12 semaines. La faisabilité (taux de recrutement, rétention et adhésion et sécurité), l’acceptabilité (questionnaire de satisfaction et entretiens semi-dirigés) et les effets potentiels (VFC, RGC, symptômes auto-rapportés, monitoring ambulatoire de pression artérielle 24h, test de marche de 6 minutes-TDM6) ont été évalués. Résultats : Une DC a été détectée chez 5 des 16 participants évalués. Il n’y a pas de différence significative entre les groupes avec (DC+) et sans (DC-) dysautonomie et aucune tendance n’a été observée. Des analyses exploratoires ont permis d’identifier des profils au sein du groupe DC+, notamment avec une DC plus prononcée pour les patients avec HC. De son côté, l’intervention a un faible taux de recrutement (10%) mais de bons taux de rétention (100%) et d’adhésion (91%) pour les 3 participants l’ayant complétée. Aucun évènement indésirable n'est survenu et l’acceptabilité par les participants a été bonne. Les effets potentiels n’ont montré aucune tendance sur la DC, alors que le TDM6 indique une amélioration de la capacité cardiovasculaire. Conclusion : Le test actif d’HO semble permettre d’identifier la DC dans la MP. Différents profils chez les patients atteints de DC pourrait être identifiés. Malgré un faible taux de recrutement, le programme de TR semble adapté et bien répondre aux besoins des personnes atteintes DC dans la MP. Néanmoins, il parait impératif d'améliorer les stratégies d'accessibilité pour atteindre une plus grande portion de la population et ainsi démontrer les effets potentiels d’un tel programme de TR."],"dc:identifier.uri":["http://hdl.handle.net/11143/21832"],"dc:language.iso":["fr","en"],"dc:publisher":["Université de Sherbrooke"],"dc:subject":["Maladie de Parkinson","Téléréadaptation","Dysautonomie","Cardiovasculaire","Parkinson’s disease","Telerehabilitation","Dysautonomia","Cardiovascular"],"dc:title":["Intervention en téléréadaptation et caractérisation de la dysautonomie cardiovasculaire dans la maladie de Parkinson"],"dc:type":["Mémoire de maîtrise"],"thesis:degree_discipline":["Réadaptation"],"thesis:degree_level":["Maîtrise"],"thesis:degree_name":["M. Sc."],"thesis:institution_name":["Faculté de médecine et des sciences de la santé"]},"updated_at":"2026-07-27T21:07:59Z"}