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South Dakota State University

The Effect of Nitrate Supplementation on Exercise Tolerance and Performance: A Systematic Review and Meta-Analysis

Abstract

dc:description.abstract

<p>The purpose of this paper was to systematically review the current literature and evaluate the overall efficacy of nitrate supplementation on exercise tolerance and performance by meta-analysis. Studies were eligible for inclusion if they met the following criteria: 1) were an experimental trial published in an English peer-reviewed journal; 2) compared the effects of inorganic nitrate consumption with a non-bioactive supplement control or placebo; 3) used a quantifiable measure of exercise performance; and 4) was carried out in apparently healthy participants without disease. A total of 29 studies were identified that investigated the effects of nitrate supplementation on exercise tolerance or performance in accordance with the criteria outlined. Analysis using time to exhaustion as the outcome variable revealed a significant effect of nitrate supplementation on exercise tolerance ES 0.27 (95% CI: 0.08 – 0.46; P = 0.004) compared to placebo. Analysis using time to complete a specific distance as the outcome variable revealed no significant effect of nitrate supplementation on performance ES 0.06 (95% CI: -0.27 – 0.15; P = 0.5) compared to placebo. Nitrate supplementation is likely to improve exercise tolerance and capacity but not exercise performance. More research is required to determine the optimal dose and duration of nitrate supplementation. It would also be important to consider the type of athlete performing the exercise, and the duration, intensity and mode of the exercise performed as these factors are likely to influence the efficacy of nitrate supplementation.</p>

Degree

thesis:*
Name thesis:degree_name
Master of Science (MS)
Level thesis:degree_level
Thesis - Open Access
Discipline thesis:degree_discipline
Health and Nutritional Sciences
Year dc:date.available
2017

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Van De Walle, Gavin
Contributors dc:contributor
  • Matthew Vukovich

Subjects

dc:subject × 6

Rights

dc:rights
Language dc:language
en

Identifiers

dc:identifier.*
Repository record dc:identifier
https://openprairie.sdstate.edu/etd/1127
OAI identifier oai:identifier
oai:openprairie.sdstate.edu:etd-2128

Chain of custody

source
Harvested from
South Dakota State University
Base URL
openprairie.sdstate.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Van De Walle, Gavin. The Effect of Nitrate Supplementation on Exercise Tolerance and Performance: A Systematic Review and Meta-Analysis. Thesis - Open Access thesis, 2017. https://openprairie.sdstate.edu/etd/1127