{"id":{"repo_id":"sdstate","oai_identifier":"oai:openprairie.sdstate.edu:etd-1853"},"canonical_url":"https://search.dev.ndltd.org/etd/sdstate/oai:openprairie.sdstate.edu:etd-1853","repository":{"repo_id":"sdstate","name":"South Dakota State University","base_url":"https://openprairie.sdstate.edu/do/oai/"},"display":{"title":"Comparative Study of Circadian Salivary Cortisol Levels in Colic and Noncolic Infants","abstract":"<p>Colic is a diagnosis of exclusion given to healthy normal infants who cry excessively. Literature review reveals that colic has been blamed by a variety of causes, none of which has been proven. Cortisol is a hormone released by the adrenal cortex. Cortisol is produced by the body according to circadian pattern as well as in response to arousing or potentially stressful events. Cortisol has been associated with infant cry behavior. This study explores the relationship between the symptoms of colic and the hormone cortisol.<br> A sample of fifty-seven infants at eight weeks of age was studied for comparisons of colic infants and noncolic infants, combined samples at two different sites. Behavioral information and salivary cortisol levels were obtained and reported using descriptive statistics. A hypothesis and research questions were formulated and tested using inferential statistics.<br> Salivary cortisol levels were obtained on noncolic and colic infants at four time points across the day. Upon analysis of this data, a significant difference was found on the mid PM time point revealing that colic infants had a lower salivary cortisol level at this time of the day then noncolic infants. Descriptive data was also collected on the noncolic and colic infants. Colic infants were found to cry more, sleep less, and spend less time awake and calm. Parents of colic infants also spent more time using comfort measures for their infants than parents of noncolic infants.<br> The following pages contain the problem and objective of the study, review of the literature, explanation of the methodology, and an analysis of the findings. Conclusions of the study provide a summary of the findings, implications for the health care provider, and recommendations for further research.</p>","abstract_html":"&lt;p&gt;Colic is a diagnosis of exclusion given to healthy normal infants who cry excessively. Literature review reveals that colic has been blamed by a variety of causes, none of which has been proven. Cortisol is a hormone released by the adrenal cortex. Cortisol is produced by the body according to circadian pattern as well as in response to arousing or potentially stressful events. Cortisol has been associated with infant cry behavior. This study explores the relationship between the symptoms of colic and the hormone cortisol.&lt;br&gt; A sample of fifty-seven infants at eight weeks of age was studied for comparisons of colic infants and noncolic infants, combined samples at two different sites. Behavioral information and salivary cortisol levels were obtained and reported using descriptive statistics. A hypothesis and research questions were formulated and tested using inferential statistics.&lt;br&gt; Salivary cortisol levels were obtained on noncolic and colic infants at four time points across the day. Upon analysis of this data, a significant difference was found on the mid PM time point revealing that colic infants had a lower salivary cortisol level at this time of the day then noncolic infants. Descriptive data was also collected on the noncolic and colic infants. Colic infants were found to cry more, sleep less, and spend less time awake and calm. Parents of colic infants also spent more time using comfort measures for their infants than parents of noncolic infants.&lt;br&gt; The following pages contain the problem and objective of the study, review of the literature, explanation of the methodology, and an analysis of the findings. Conclusions of the study provide a summary of the findings, implications for the health care provider, and recommendations for further research.&lt;/p&gt;","abstract_has_math":false,"creators":["Hogue, Alisa L."],"institution":null,"degree_name":"Master of Science (MS)","degree_level":"Thesis - University Access Only","degree_discipline":"Graduate Nursing","degree_department":null,"school":null,"contributors":["Margaret Hegge"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1999,"date_issued":"1999-01-01T08:00:00Z","date_published":"1999-01-01T08:00:00Z","updated_at":"2026-07-24T04:28:23Z","subjects":["hydrocortisone","coilic","health and hygiene of infants","Nursing"],"languages":["en"],"rights":["Copyright © 1999 Alisa Hogue. All rights reserved"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://openprairie.sdstate.edu/etd/853","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Margaret Hegge"]},{"key":"dc:creator","label":"Author","values":["Hogue, Alisa L."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Graduate Nursing"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis - University Access Only"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MS)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["hydrocortisone","coilic","health and hygiene of infants","Nursing"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright © 1999 Alisa Hogue. All rights reserved"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://openprairie.sdstate.edu/etd/853"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["<p>Colic is a diagnosis of exclusion given to healthy normal infants who cry excessively. Literature review reveals that colic has been blamed by a variety of causes, none of which has been proven. Cortisol is a hormone released by the adrenal cortex. Cortisol is produced by the body according to circadian pattern as well as in response to arousing or potentially stressful events. Cortisol has been associated with infant cry behavior. This study explores the relationship between the symptoms of colic and the hormone cortisol.<br> A sample of fifty-seven infants at eight weeks of age was studied for comparisons of colic infants and noncolic infants, combined samples at two different sites. Behavioral information and salivary cortisol levels were obtained and reported using descriptive statistics. A hypothesis and research questions were formulated and tested using inferential statistics.<br> Salivary cortisol levels were obtained on noncolic and colic infants at four time points across the day. Upon analysis of this data, a significant difference was found on the mid PM time point revealing that colic infants had a lower salivary cortisol level at this time of the day then noncolic infants. Descriptive data was also collected on the noncolic and colic infants. Colic infants were found to cry more, sleep less, and spend less time awake and calm. Parents of colic infants also spent more time using comfort measures for their infants than parents of noncolic infants.<br> The following pages contain the problem and objective of the study, review of the literature, explanation of the methodology, and an analysis of the findings. Conclusions of the study provide a summary of the findings, implications for the health care provider, and recommendations for further research.</p>"]},{"key":"dc:title","label":"Title","values":["Comparative Study of Circadian Salivary Cortisol Levels in Colic and Noncolic Infants"]}]}],"canonical_facts":{"dc:contributor":["Margaret Hegge"],"dc:creator":["Hogue, Alisa L."],"dc:description.abstract":["<p>Colic is a diagnosis of exclusion given to healthy normal infants who cry excessively. Literature review reveals that colic has been blamed by a variety of causes, none of which has been proven. Cortisol is a hormone released by the adrenal cortex. Cortisol is produced by the body according to circadian pattern as well as in response to arousing or potentially stressful events. Cortisol has been associated with infant cry behavior. This study explores the relationship between the symptoms of colic and the hormone cortisol.<br> A sample of fifty-seven infants at eight weeks of age was studied for comparisons of colic infants and noncolic infants, combined samples at two different sites. Behavioral information and salivary cortisol levels were obtained and reported using descriptive statistics. A hypothesis and research questions were formulated and tested using inferential statistics.<br> Salivary cortisol levels were obtained on noncolic and colic infants at four time points across the day. Upon analysis of this data, a significant difference was found on the mid PM time point revealing that colic infants had a lower salivary cortisol level at this time of the day then noncolic infants. Descriptive data was also collected on the noncolic and colic infants. Colic infants were found to cry more, sleep less, and spend less time awake and calm. Parents of colic infants also spent more time using comfort measures for their infants than parents of noncolic infants.<br> The following pages contain the problem and objective of the study, review of the literature, explanation of the methodology, and an analysis of the findings. Conclusions of the study provide a summary of the findings, implications for the health care provider, and recommendations for further research.</p>"],"dc:identifier":["https://openprairie.sdstate.edu/etd/853"],"dc:language":["en"],"dc:rights":["Copyright © 1999 Alisa Hogue. All rights reserved"],"dc:subject":["hydrocortisone","coilic","health and hygiene of infants","Nursing"],"dc:title":["Comparative Study of Circadian Salivary Cortisol Levels in Colic and Noncolic Infants"],"thesis:degree_discipline":["Graduate Nursing"],"thesis:degree_level":["Thesis - University Access Only"],"thesis:degree_name":["Master of Science (MS)"]},"updated_at":"2026-07-24T04:28:23Z"}