Pigment granules in melanocytes of Fundulus heteroclitus exhibit both local movements and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum which expands and contracts to move them; the state of the continuum is the resultant of a dynamic equilibrium between expansile and contractile forces manifested in the local movements of granules. The fine structure of the cell has been explored by electron microscopy; the prominent features of the cell are microtubules. Several alternatives for the specific granule moving apparatus have been discussed. In the light of these studies, previous theories of the mechanism of granule movement have been ruled unlikely.
","abstract_html":"<p>Pigment granules in melanocytes of Fundulus heteroclitus exhibit both local movements and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum which expands and contracts to move them; the state of the continuum is the resultant of a dynamic equilibrium between expansile and contractile forces manifested in the local movements of granules. The fine structure of the cell has been explored by electron microscopy; the prominent features of the cell are microtubules. Several alternatives for the specific granule moving apparatus have been discussed. In the light of these studies, previous theories of the mechanism of granule movement have been ruled unlikely.</p>","abstract_has_math":false,"creators":["Green, Lorna"],"institution":null,"degree_name":"Doctor of Philosophy (PhD)","degree_level":"Thesis","degree_discipline":null,"degree_department":null,"school":null,"contributors":["Paul Weiss"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1965,"date_issued":"1965-01-01T08:00:00Z","date_published":"1965-01-01T08:00:00Z","updated_at":"2026-07-24T04:11:51Z","subjects":["melanocytes","pigment granules","intracellular movement","Fundulus heteroclitus","microtubules","hormone response","Life Sciences"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/580","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Paul Weiss"]},{"key":"dc:creator","label":"Author","values":["Green, Lorna"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Doctor of Philosophy (PhD)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["melanocytes","pigment granules","intracellular movement","Fundulus heteroclitus","microtubules","hormone response","Life Sciences"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/580"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Pigment granules in melanocytes of Fundulus heteroclitus exhibit both local movements and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum which expands and contracts to move them; the state of the continuum is the resultant of a dynamic equilibrium between expansile and contractile forces manifested in the local movements of granules. The fine structure of the cell has been explored by electron microscopy; the prominent features of the cell are microtubules. Several alternatives for the specific granule moving apparatus have been discussed. In the light of these studies, previous theories of the mechanism of granule movement have been ruled unlikely.
"]},{"key":"dc:title","label":"Title","values":["Studies on the Granule-Moving System of Melanocytes of Fundulus Heteroclitus"]}]}],"canonical_facts":{"dc:contributor":["Paul Weiss"],"dc:creator":["Green, Lorna"],"dc:description.abstract":["Pigment granules in melanocytes of Fundulus heteroclitus exhibit both local movements and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum which expands and contracts to move them; the state of the continuum is the resultant of a dynamic equilibrium between expansile and contractile forces manifested in the local movements of granules. The fine structure of the cell has been explored by electron microscopy; the prominent features of the cell are microtubules. Several alternatives for the specific granule moving apparatus have been discussed. In the light of these studies, previous theories of the mechanism of granule movement have been ruled unlikely.
"],"dc:identifier":["https://digitalcommons.rockefeller.edu/student_theses_and_dissertations/580"],"dc:subject":["melanocytes","pigment granules","intracellular movement","Fundulus heteroclitus","microtubules","hormone response","Life Sciences"],"dc:title":["Studies on the Granule-Moving System of Melanocytes of Fundulus Heteroclitus"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Doctor of Philosophy (PhD)"]},"updated_at":"2026-07-24T04:11:51Z"}