SYNTHETIC STUDIES ON THE SAFRAMYCINS A, B AND S: A TOTAL SYNTHESIS OF SAFRAMYCIN B
type: CreativeWork
description: The Saframycins are naturally occurring antibiotics with an interesting bisquinone structure. The first and only synthesis of saframycin B is described herein. The interesting aspects of this synthesis are the convergent approach and the method of stereochemical control. Studies directed towards adapting the saframycin B synthesis to the synthesis of saframycins A and S are also described. These studies have resulted in the synthesis of a compound structurally related to the saframycins but so far unreported in the literature. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)
abstract: The Saframycins are naturally occurring antibiotics with an interesting bisquinone structure. The first and only synthesis of saframycin B is described herein. The interesting aspects of this synthesis are the convergent approach and the method of stereochemical control. Studies directed towards adapting the saframycin B synthesis to the synthesis of saframycins A and S are also described. These studies have resulted in the synthesis of a compound structurally related to the saframycins but so far unreported in the literature. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)
author: SACHLEBEN, RICHARD ALAN
language: eng
keywords: Organic chemistry
date published: 1985
date modified: 2026-07-24T04:10:21Z
provider: Rice University
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: Rice University

PropertyValue
property ID: Handle
value: https://hdl.handle.net/1911/15930