{"id":{"repo_id":"regina","oai_identifier":"oai:uregina.scholaris.ca:10294/16095"},"canonical_url":"https://search.dev.ndltd.org/etd/regina/oai:uregina.scholaris.ca:10294/16095","repository":{"repo_id":"regina","name":"University of Regina","base_url":"https://uregina.scholaris.ca/server/oai/request"},"display":{"title":"Effect of creatine monohydrate supplementation in aging adults with type II diabetes","abstract":"Sarcopenia generally refers to the age-related reduction in muscle strength and physical performance, with greater decreases found in aging adults with type II diabetes (T2D). Supplementing with creatine, a nitrogen-containing compound formed from reactions involving the amino acids arginine, glycine and methionine, is an intervention which have been shown to increase muscle strength, endurance and physical performance in healthy aging adults. Further, creatine supplementation has been shown to influence glucose metabolism in individuals with T2D. However, the effects of creatine supplementation in aging adults with T2D in unknown. Therefore, the purpose of this study was to examine the effects of creatine supplementation on measures of blood glucose, muscle strength, endurance and tasks of physical performance in aging adults with T2D. Using a double-blind, repeated measures design, participants were randomized to supplement with creatine monohydrate (CR: n = 4; 71 ± 7 years, 94.3 ± 13.9 kg, 165.2 ± 6.0 cm; 0.3 g·kg -1·day -1) or placebo (PLA: n = 3; 74 ± 2 years, 95.2 ± 7.3 kg, 159.3 ± 9.5cm; 0.3 g·kg -1·day -1 maltodextrin) for seven consecutive days. Prior to and following supplementation, variables measured were fasting blood glucose, muscle strength (1-repetition maximum leg press, chest press, hand-grip), muscle endurance (leg press and chest press; maximal number of repetitions performed at 50% baseline 1-repetittion maximum), and tests of physical performance (6-minute walk test, sit-to-stand chair test). Results showed that both groups experienced similar changes in all measures over time. In conclusion, in this preliminary investigation, creatine supplementation had no effect on blood glucose or measures of muscle strength, endurance and physical performance in aging adults with T2D. Key words: sarcopenia, blood glucose, strength, physical performance","abstract_html":"Sarcopenia generally refers to the age-related reduction in muscle strength and physical performance, with greater decreases found in aging adults with type II diabetes (T2D). Supplementing with creatine, a nitrogen-containing compound formed from reactions involving the amino acids arginine, glycine and methionine, is an intervention which have been shown to increase muscle strength, endurance and physical performance in healthy aging adults. Further, creatine supplementation has been shown to influence glucose metabolism in individuals with T2D. However, the effects of creatine supplementation in aging adults with T2D in unknown. Therefore, the purpose of this study was to examine the effects of creatine supplementation on measures of blood glucose, muscle strength, endurance and tasks of physical performance in aging adults with T2D. Using a double-blind, repeated measures design, participants were randomized to supplement with creatine monohydrate (CR: n = 4; 71 ± 7 years, 94.3 ± 13.9 kg, 165.2 ± 6.0 cm; 0.3 g·kg -1·day -1) or placebo (PLA: n = 3; 74 ± 2 years, 95.2 ± 7.3 kg, 159.3 ± 9.5cm; 0.3 g·kg -1·day -1 maltodextrin) for seven consecutive days. Prior to and following supplementation, variables measured were fasting blood glucose, muscle strength (1-repetition maximum leg press, chest press, hand-grip), muscle endurance (leg press and chest press; maximal number of repetitions performed at 50% baseline 1-repetittion maximum), and tests of physical performance (6-minute walk test, sit-to-stand chair test). Results showed that both groups experienced similar changes in all measures over time. In conclusion, in this preliminary investigation, creatine supplementation had no effect on blood glucose or measures of muscle strength, endurance and physical performance in aging adults with T2D. Key words: sarcopenia, blood glucose, strength, physical performance","abstract_has_math":false,"creators":["Bailie, Robert David"],"institution":"Faculty of Graduate Studies and Research, University of Regina","degree_name":"Master of Science (MSc)","degree_level":"Master's","degree_discipline":"Kinesiology and Health Studies","degree_department":null,"school":null,"contributors":[],"advisors":["Candow, Darren"],"committee_chairs":[],"committee_members":["Totosy de Zepetnek, Julia","Little, Jonathan"],"year":2023,"date_issued":"2023-02","date_published":"2023-02","updated_at":"2026-07-24T04:03:45Z","subjects":["Sarcopenia","Blood glucose","Strength","Physical performance"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier.doi","label":"DOI","values":["https://doi.org/10.82465/4857"],"render_values":[{"text":"https://doi.org/10.82465/4857","href":"https://doi.org/10.82465/4857","code":true}]}]},"links":{"outbound_url":"https://hdl.handle.net/10294/16095","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Candow, Darren"]},{"key":"dc:contributor.committeemember","label":"Committee Member","values":["Totosy de Zepetnek, Julia","Little, Jonathan"]},{"key":"dc:creator","label":"Author","values":["Bailie, Robert David"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2023-07-18T21:28:01Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2023-07-18T21:28:01Z"]},{"key":"dc:date.issued","label":"Date","values":["2023-02"]},{"key":"dc:publisher","label":"Institution","values":["Faculty of Graduate Studies and Research, University of Regina"]},{"key":"dc:type","label":"Dc Type","values":["master thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology and Health Studies"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Master's"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (MSc)"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Faculty of Graduate Studies and Research, University of Regina"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Sarcopenia","Blood glucose","Strength","Physical performance"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.doi","label":"DOI","values":["https://doi.org/10.82465/4857"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://hdl.handle.net/10294/16095"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["A Thesis Submitted to the Faculty of Graduate Studies and Research In Partial Fulfillment of the Requirements for the Degree of Master of Science in Kinesiology and Health Studies, University of Regina. v, 58 p."]},{"key":"dc:description.abstract","label":"Abstract","values":["Sarcopenia generally refers to the age-related reduction in muscle strength and physical performance, with greater decreases found in aging adults with type II diabetes (T2D). Supplementing with creatine, a nitrogen-containing compound formed from reactions involving the amino acids arginine, glycine and methionine, is an intervention which have been shown to increase muscle strength, endurance and physical performance in healthy aging adults. Further, creatine supplementation has been shown to influence glucose metabolism in individuals with T2D. However, the effects of creatine supplementation in aging adults with T2D in unknown. Therefore, the purpose of this study was to examine the effects of creatine supplementation on measures of blood glucose, muscle strength, endurance and tasks of physical performance in aging adults with T2D. Using a double-blind, repeated measures design, participants were randomized to supplement with creatine monohydrate (CR: n = 4; 71 ± 7 years, 94.3 ± 13.9 kg, 165.2 ± 6.0 cm; 0.3 g·kg -1·day -1) or placebo (PLA: n = 3; 74 ± 2 years, 95.2 ± 7.3 kg, 159.3 ± 9.5cm; 0.3 g·kg -1·day -1 maltodextrin) for seven consecutive days. Prior to and following supplementation, variables measured were fasting blood glucose, muscle strength (1-repetition maximum leg press, chest press, hand-grip), muscle endurance (leg press and chest press; maximal number of repetitions performed at 50% baseline 1-repetittion maximum), and tests of physical performance (6-minute walk test, sit-to-stand chair test). Results showed that both groups experienced similar changes in all measures over time. In conclusion, in this preliminary investigation, creatine supplementation had no effect on blood glucose or measures of muscle strength, endurance and physical performance in aging adults with T2D. Key words: sarcopenia, blood glucose, strength, physical performance"]},{"key":"dc:title","label":"Title","values":["Effect of creatine monohydrate supplementation in aging adults with type II diabetes"]}]}],"canonical_facts":{"dc:contributor.advisor":["Candow, Darren"],"dc:contributor.committeemember":["Totosy de Zepetnek, Julia","Little, Jonathan"],"dc:creator":["Bailie, Robert David"],"dc:date.accessioned":["2023-07-18T21:28:01Z"],"dc:date.available":["2023-07-18T21:28:01Z"],"dc:date.issued":["2023-02"],"dc:description":["A Thesis Submitted to the Faculty of Graduate Studies and Research In Partial Fulfillment of the Requirements for the Degree of Master of Science in Kinesiology and Health Studies, University of Regina. v, 58 p."],"dc:description.abstract":["Sarcopenia generally refers to the age-related reduction in muscle strength and physical performance, with greater decreases found in aging adults with type II diabetes (T2D). Supplementing with creatine, a nitrogen-containing compound formed from reactions involving the amino acids arginine, glycine and methionine, is an intervention which have been shown to increase muscle strength, endurance and physical performance in healthy aging adults. Further, creatine supplementation has been shown to influence glucose metabolism in individuals with T2D. However, the effects of creatine supplementation in aging adults with T2D in unknown. Therefore, the purpose of this study was to examine the effects of creatine supplementation on measures of blood glucose, muscle strength, endurance and tasks of physical performance in aging adults with T2D. Using a double-blind, repeated measures design, participants were randomized to supplement with creatine monohydrate (CR: n = 4; 71 ± 7 years, 94.3 ± 13.9 kg, 165.2 ± 6.0 cm; 0.3 g·kg -1·day -1) or placebo (PLA: n = 3; 74 ± 2 years, 95.2 ± 7.3 kg, 159.3 ± 9.5cm; 0.3 g·kg -1·day -1 maltodextrin) for seven consecutive days. Prior to and following supplementation, variables measured were fasting blood glucose, muscle strength (1-repetition maximum leg press, chest press, hand-grip), muscle endurance (leg press and chest press; maximal number of repetitions performed at 50% baseline 1-repetittion maximum), and tests of physical performance (6-minute walk test, sit-to-stand chair test). Results showed that both groups experienced similar changes in all measures over time. In conclusion, in this preliminary investigation, creatine supplementation had no effect on blood glucose or measures of muscle strength, endurance and physical performance in aging adults with T2D. Key words: sarcopenia, blood glucose, strength, physical performance"],"dc:identifier.doi":["https://doi.org/10.82465/4857"],"dc:identifier.uri":["https://hdl.handle.net/10294/16095"],"dc:language.iso":["en"],"dc:publisher":["Faculty of Graduate Studies and Research, University of Regina"],"dc:subject":["Sarcopenia","Blood glucose","Strength","Physical performance"],"dc:title":["Effect of creatine monohydrate supplementation in aging adults with type II diabetes"],"dc:type":["master thesis"],"thesis:degree_discipline":["Kinesiology and Health Studies"],"thesis:degree_level":["Master's"],"thesis:degree_name":["Master of Science (MSc)"],"thesis:institution_name":["Faculty of Graduate Studies and Research, University of Regina"]},"updated_at":"2026-07-24T04:03:45Z"}