DIETARY AND EXERCISE EFFECTS ON NEURAL RESPONSES TO VISUAL FOOD STIMULI IN OVERWEIGHT AND OBESE ADULTS

Results from human neuroimaging studies consistently demonstrate that obesity is associated with altered neural reward processing of food-relevant cues. These observations have caused some investigators to question whether behavioral interventions such as dietary manipulations or physical activity might modulate processing of food cues in reward-related brain regions. The use of functional magnetic resonance imaging (fMRI) to measure neural responses to visual food stimuli is a commonly utilized paradigm for assessing neural reward responses relating to ingestive behavior of foods in humans. Using this study design, limited evidence suggests that increases in dietary protein and participation in acute and chronic aerobic exercise may modulate reward-related neural responses to visual food stimuli. However, data regarding the reliability of this fMRI-based paradigm to produce consistent results on multiple testing days and time course of responses following a meal have not been systematically studied. These data are critically important for the proper interpretation of existing literature and for the design of future intervention studies using this paradigm.

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Nutrition Science

Year

2015

Author dc:creator

• Sayer, Richard

Contributors dc:contributor

• Wayne W Campbell
• David A Kareken
• Thomas M Talavage
• Megan A McCrory

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1429

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2645