{"id":{"repo_id":"purdue-thes","oai_identifier":"oai:docs.lib.purdue.edu:open_access_dissertations-2426"},"canonical_url":"https://search.dev.ndltd.org/etd/purdue-thes/oai:docs.lib.purdue.edu:open_access_dissertations-2426","repository":{"repo_id":"purdue-thes","name":"Purdue University","base_url":"https://docs.lib.purdue.edu/do/oai/"},"display":{"title":"UNDERSTANDING AND EVALUATING CRYSTAL POLYMORPHISM BY SECOND HARMONIC GENERATION MICROSCOPY","abstract":"The crystalline form of a solid can profoundly affect its physical and chemical properties, with both potentially stable and metastable crystal polymorphs are accessible during crystal formation. Conventional methods limit the detection of rare nucleation and rapid phase transitioning events due to their lack of selectivity and sensitivity. Inkjet printing of a solution confines the nucleation event in a few micrometer volumes within the droplet, and furthermore rapid desolvation favors the kinetic factor to trap the rare metastable polymorphs. Second harmonic generation microscopy (SHG) possesses enough sensitivity to detect sub-micrometer size chiral crystals selectively and has the potential for use in crystal nucleation studies.","abstract_html":"The crystalline form of a solid can profoundly affect its physical and chemical properties, with both potentially stable and metastable crystal polymorphs are accessible during crystal formation. Conventional methods limit the detection of rare nucleation and rapid phase transitioning events due to their lack of selectivity and sensitivity. Inkjet printing of a solution confines the nucleation event in a few micrometer volumes within the droplet, and furthermore rapid desolvation favors the kinetic factor to trap the rare metastable polymorphs. Second harmonic generation microscopy (SHG) possesses enough sensitivity to detect sub-micrometer size chiral crystals selectively and has the potential for use in crystal nucleation studies.","abstract_has_math":false,"creators":["Chowdhury, Azhad Chowdhury"],"institution":null,"degree_name":"Doctor of Philosophy (PhD)","degree_level":"Dissertation","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Garth J Simpson","Mary J Wirth","Chittaranjan Das","Lynne S Taylor"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016-01-01T08:00:00Z","date_published":"2016-01-01T08:00:00Z","updated_at":"2026-07-24T03:54:31Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://docs.lib.purdue.edu/open_access_dissertations/1210","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Garth J Simpson","Mary J Wirth","Chittaranjan Das","Lynne S Taylor"]},{"key":"dc:creator","label":"Author","values":["Chowdhury, Azhad Chowdhury"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Doctor of Philosophy (PhD)"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://docs.lib.purdue.edu/open_access_dissertations/1210"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The crystalline form of a solid can profoundly affect its physical and chemical properties, with both potentially stable and metastable crystal polymorphs are accessible during crystal formation. Conventional methods limit the detection of rare nucleation and rapid phase transitioning events due to their lack of selectivity and sensitivity. Inkjet printing of a solution confines the nucleation event in a few micrometer volumes within the droplet, and furthermore rapid desolvation favors the kinetic factor to trap the rare metastable polymorphs. Second harmonic generation microscopy (SHG) possesses enough sensitivity to detect sub-micrometer size chiral crystals selectively and has the potential for use in crystal nucleation studies."]},{"key":"dc:title","label":"Title","values":["UNDERSTANDING AND EVALUATING CRYSTAL POLYMORPHISM BY SECOND HARMONIC GENERATION MICROSCOPY"]}]}],"canonical_facts":{"dc:contributor":["Garth J Simpson","Mary J Wirth","Chittaranjan Das","Lynne S Taylor"],"dc:creator":["Chowdhury, Azhad Chowdhury"],"dc:description.abstract":["The crystalline form of a solid can profoundly affect its physical and chemical properties, with both potentially stable and metastable crystal polymorphs are accessible during crystal formation. Conventional methods limit the detection of rare nucleation and rapid phase transitioning events due to their lack of selectivity and sensitivity. Inkjet printing of a solution confines the nucleation event in a few micrometer volumes within the droplet, and furthermore rapid desolvation favors the kinetic factor to trap the rare metastable polymorphs. Second harmonic generation microscopy (SHG) possesses enough sensitivity to detect sub-micrometer size chiral crystals selectively and has the potential for use in crystal nucleation studies."],"dc:identifier":["https://docs.lib.purdue.edu/open_access_dissertations/1210"],"dc:title":["UNDERSTANDING AND EVALUATING CRYSTAL POLYMORPHISM BY SECOND HARMONIC GENERATION MICROSCOPY"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Doctor of Philosophy (PhD)"]},"updated_at":"2026-07-24T03:54:31Z"}