Mass Spectrometric Studies on Lignin Sequencing and Fast Pyrolysis, Functional-Group Selective Ion-Molecule Reactions and Reactivity of Bi- and Triradicals

Due to the high sensitivity, selectivity and speed, mass spectrometry (MS) has proved to be an invaluable tool for mixture analysis and structural elucidation of mixture components. Tandem mass spectrometry (MS/MS) utilizing collision-activated dissociation (CAD) has become the technique of choice for structural elucidation of unknown analytes. The coupling of MS/MS with high performance liquid chromatography (HPLC) has allowed trace level analysis of components in very complex mixtures. Analysis of mixtures of lignin degradation products is a problematic area for mass spectrometry due to the highly complex lignin linkages present. Hence, study of lignin model compounds with varies linkage types is very helpful for the structural elucidation of unnknown lignins. Gas phase ion-molecule reaction can be useful in study of reaction kinetics and mechanism and even in probing the functional groups in unknown molecules. The functional group selective ion-molecule reaction has great potential for unknown drug metabolite identification

Name thesis:degree_name

Doctor of Philosophy (PhD)

Level thesis:degree_level

Dissertation

Discipline thesis:degree_discipline

Chemistry

Year

2014

Author dc:creator

• Sheng, Huaming

Contributors dc:contributor

• Hilkka I Kenttämaa
• Scott A. McLuckey
• Chengde Mao
• Yu Xia

• Fast Pyrolysis
• Ion-molecule Reactions
• Lignin Sequencing
• Mass Spectrometer
• Tri-radicals

Repository record dc:identifier

https://docs.lib.purdue.edu/open_access_dissertations/1068

OAI identifier oai:identifier

oai:docs.lib.purdue.edu:open_access_dissertations-2284