{"id":{"repo_id":"plymouth","oai_identifier":"oai:pearl.plymouth.ac.uk:pms-theses-1043"},"canonical_url":"https://search.dev.ndltd.org/etd/plymouth/oai:pearl.plymouth.ac.uk:pms-theses-1043","repository":{"repo_id":"plymouth","name":"University of Plymouth","base_url":"https://pearl.plymouth.ac.uk/do/oai"},"display":{"title":"Anastomotic leakage in rectal surgery: Where are we and where do we go from here?","abstract":"Anastomotic leak in colorectal surgery is a significant complication which is feared by surgeons and has considerable consequences for patients. It affects up to 17% of rectal resections and although there is significant knowledge regarding its detection and treatment, there are still no reliable methods for its prevention. We proposed the routine use of intra-operative endoscopy as a method of reducing the risk of anastomotic leak. This thesis explores current knowledge regarding anastomotic leaks, including the causes, prevention and management. We also present the findings from a feasibility trial into intra-operative endoscopy as a method for reducing anastomotic leak rate. We found that the prevention of anastomotic leak is multi-faceted. Current methods cannot prevent it entirely but intra-operative endoscopy is a safe and potentially beneficial method of identifying leaks and preventing complications but further large-scale trials are required. If it cannot be prevented, early diagnosis and treatment is important to reduce further complications.","abstract_html":"Anastomotic leak in colorectal surgery is a significant complication which is feared by surgeons and has considerable consequences for patients. It affects up to 17% of rectal resections and although there is significant knowledge regarding its detection and treatment, there are still no reliable methods for its prevention. We proposed the routine use of intra-operative endoscopy as a method of reducing the risk of anastomotic leak. This thesis explores current knowledge regarding anastomotic leaks, including the causes, prevention and management. We also present the findings from a feasibility trial into intra-operative endoscopy as a method for reducing anastomotic leak rate. We found that the prevention of anastomotic leak is multi-faceted. Current methods cannot prevent it entirely but intra-operative endoscopy is a safe and potentially beneficial method of identifying leaks and preventing complications but further large-scale trials are required. If it cannot be prevented, early diagnosis and treatment is important to reduce further complications.","abstract_has_math":false,"creators":["Rossi, Benjamin William Peter"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Mark Coleman, Sebastian Smolarek, Simon Rule"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2023,"date_issued":"2023-01-01T08:00:00Z","date_published":"2023-01-01T08:00:00Z","updated_at":"2026-07-24T03:50:32Z","subjects":["Anastomotic leak Colorectal surgery"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["10026.1/21877"],"render_values":[{"text":"10026.1/21877","href":null,"code":true}]}]},"links":{"outbound_url":"https://pearl.plymouth.ac.uk/pms-theses/44","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Mark Coleman, Sebastian Smolarek, Simon Rule"]},{"key":"dc:creator","label":"Author","values":["Rossi, Benjamin William Peter"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2025-01-05T08:00:00Z"]},{"key":"dc:date.issued","label":"Date","values":["2023-01-01T08:00:00Z"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Anastomotic leak Colorectal surgery"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10026.1/21877","https://pearl.plymouth.ac.uk/pms-theses/44"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Anastomotic leak in colorectal surgery is a significant complication which is feared by surgeons and has considerable consequences for patients. It affects up to 17% of rectal resections and although there is significant knowledge regarding its detection and treatment, there are still no reliable methods for its prevention. We proposed the routine use of intra-operative endoscopy as a method of reducing the risk of anastomotic leak. This thesis explores current knowledge regarding anastomotic leaks, including the causes, prevention and management. We also present the findings from a feasibility trial into intra-operative endoscopy as a method for reducing anastomotic leak rate. We found that the prevention of anastomotic leak is multi-faceted. Current methods cannot prevent it entirely but intra-operative endoscopy is a safe and potentially beneficial method of identifying leaks and preventing complications but further large-scale trials are required. If it cannot be prevented, early diagnosis and treatment is important to reduce further complications."]},{"key":"dc:title","label":"Title","values":["Anastomotic leakage in rectal surgery: Where are we and where do we go from here?"]}]}],"canonical_facts":{"dc:contributor":["Mark Coleman, Sebastian Smolarek, Simon Rule"],"dc:creator":["Rossi, Benjamin William Peter"],"dc:date.available":["2025-01-05T08:00:00Z"],"dc:date.issued":["2023-01-01T08:00:00Z"],"dc:description.abstract":["Anastomotic leak in colorectal surgery is a significant complication which is feared by surgeons and has considerable consequences for patients. It affects up to 17% of rectal resections and although there is significant knowledge regarding its detection and treatment, there are still no reliable methods for its prevention. We proposed the routine use of intra-operative endoscopy as a method of reducing the risk of anastomotic leak. This thesis explores current knowledge regarding anastomotic leaks, including the causes, prevention and management. We also present the findings from a feasibility trial into intra-operative endoscopy as a method for reducing anastomotic leak rate. We found that the prevention of anastomotic leak is multi-faceted. Current methods cannot prevent it entirely but intra-operative endoscopy is a safe and potentially beneficial method of identifying leaks and preventing complications but further large-scale trials are required. If it cannot be prevented, early diagnosis and treatment is important to reduce further complications."],"dc:identifier":["10026.1/21877","https://pearl.plymouth.ac.uk/pms-theses/44"],"dc:language":["eng"],"dc:subject":["Anastomotic leak Colorectal surgery"],"dc:title":["Anastomotic leakage in rectal surgery: Where are we and where do we go from here?"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T03:50:32Z"}