Monolayer Studies of Mixed Films Containing Cerebrosides by Surface Tensiometry and Brewster Angle Microscopy

In this work surface pressure-area isotherms and Brewster angle microscope (BAM) images were obtained for two-component Langmuir monolayers of bovine and porcine cerebrosides with cholesterol and palmitic acid (PA), respectively, at the air-water interface. BAM images of bovine and porcine cerebrosides reveal that condensed films form at low surface pressures. Collapse of cerebroside films resulted in line-shaped 2-D and 3-D structures. Introduction of cholesterol into bovine cerebrosides monolayers resulted in more loosely packed domains. A similar trend was observed upon the addition of PA to porcine cerebrosides. Surface morphology, collapse pressures, and collapse structures of binary films was dependent upon cholesterol or PA content. Deviations from the additivity of area and variation in collapse pressures indicate that films of cholesterol/bovine cerebrosides and PA/porcine cerebrosides are miscible.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Chemistry

Grantor dc:publisher

The Ohio State University

Year dc:date

2013

Author dc:creator

• Adams, Ellen M.

Contributors dc:contributor

• Allen, Heather C.

• Chemistry

Statement dc:rights

• unrestricted
• This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.

Language dc:language

English

Repository record dc:identifier

http://rave.ohiolink.edu/etdc/view?acc_num=osu1365512873

OAI identifier oai:identifier

oai:etd.ohiolink.edu:osu1365512873