Validation and Repeatability of Pediatric Refractive Error Profile 2 (PREP2)

Many myopia control studies use refractive correction as a means to slow axialgrowth. The Pediatric Refractive Error Profile (PREP) is a survey used to measure qualityof life of children wearing refractive correction and can be used in these studies. ThePREP2 is an updated version of this survey. The purpose of this study is to compare therepeatability and validity of the PREP2 to the PREP.This was done by having subjects take two administrations of the each survey,separated by a week. On the initial visit, the parents also completed a survey of how theybelieved their child felt about his or her vision correction. Each survey was scored andthe repeatability was established using Student’s t-test, 95% limits of agreement, Bland-Altman mean versus difference plots, and Pearson’s Correlation Coefficient. The validitywas established by comparing correlation to the parent survey with Pearson’s CorrelationCoefficient and comparing internal consistency within scales.We examined 25 glasses wearers and 20 contact lens wearers between the ages ofeight and 14. There was no significant bias between the two administrations of the PREPor PREP2 on any scale except on the PREP Academics scale for glasses wearers(p=0.002). The limits of agreement of glasses wearers for the PREP ranged from ±26.5 to±57.7, contact lens wearers for the PREP ranged from ±16.1 to ±34.7, glasses wearers forthe PREP2 ranged from ±20.0 to ±33.8, and contact lens wearers for the PREP2 rangedfrom ±15.2 to ±25.3. Using Pearson’s Correlation Coefficient, all scales of the PREP and PREP2 were statistically significant with the exception of Near Vision of PREP forspectacle wearers (p=0.166). The correlation to the parent’s survey was statisticallysignificant for Handling (p=<0.001) for the PREP and Overall Vision (p=<0.001),Appearance (p=0.001), and Activities (p=0.001) for the PREP2. The internal consistencywas greater than 0.70 for Overall Vision, Appearance, Distance Vision, and Academicsfor the PREP and on all scales for the PREP2.The PREP2 has higher repeatability and validity than the PREP and is a bettersurvey for following quality of life changes over time. Further studies need to beconducted to eliminate questions from each scale, determine the scalability via Raschanalysis, and validate the PREP2 in subjects wearing orthokeratology lenses.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Vision Science

Grantor dc:publisher

The Ohio State University

Year dc:date

2013

Author dc:creator

• Andersen, Courtney Erin

Contributors dc:contributor

• Walline, Jeffrey J.

• Health Sciences
• PREP
• Myopia Control
• Pediatrics

Statement dc:rights

• unrestricted
• This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.

Language dc:language

English

Repository record dc:identifier

http://rave.ohiolink.edu/etdc/view?acc_num=osu1363117173

OAI identifier oai:identifier

oai:etd.ohiolink.edu:osu1363117173