{"id":{"repo_id":"ohiolink","oai_identifier":"oai:etd.ohiolink.edu:case1347309212"},"canonical_url":"https://search.dev.ndltd.org/etd/ohiolink/oai:etd.ohiolink.edu:case1347309212","repository":{"repo_id":"ohiolink","name":"OhioLINK","base_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/oai/oai"},"display":{"title":"Characteristics and usefulness of interfascicular contacts in peripheral nerve recording","abstract":"Neural interfaces have been used in conjunction with source separationalgorithms to address the challenge of extracting useful command signals fromnerves. A peripheral nerve interface is generally useful for signal extraction if it (1) exhibits favorable recording characteristics such as signal-to-noise ratio and (2) provides as many independent channels of neural information as possible. We investigated the usefulness of novel interfascicular electrodes in acute experiments on the rabbit sciatic nerve (n = 4). Directed interfascicular contacts were found to record compound action potentials (CAPs) with a meanSNR (at p = 0.05) of 24.5 dB with respect to interference sources. Contacts that (1)faced opposite directions and (2) were placed in various positions within theepineurium were found to record independent information from the nerve (mixing matrix |det(H)|>0.05 for all electrode configurations). This neuralinformation recorded using interfascicular electrodes may potentially be useful forcommand signal extraction algorithms.","abstract_html":"Neural interfaces have been used in conjunction with source separationalgorithms to address the challenge of extracting useful command signals fromnerves. A peripheral nerve interface is generally useful for signal extraction if it (1) exhibits favorable recording characteristics such as signal-to-noise ratio and (2) provides as many independent channels of neural information as possible. We investigated the usefulness of novel interfascicular electrodes in acute experiments on the rabbit sciatic nerve (n = 4). Directed interfascicular contacts were found to record compound action potentials (CAPs) with a meanSNR (at p = 0.05) of 24.5 dB with respect to interference sources. Contacts that (1)faced opposite directions and (2) were placed in various positions within theepineurium were found to record independent information from the nerve (mixing matrix |det(H)|>0.05 for all electrode configurations). This neuralinformation recorded using interfascicular electrodes may potentially be useful forcommand signal extraction algorithms.","abstract_has_math":false,"creators":["Kolb, Ilya"],"institution":"Case Western Reserve University School of Graduate Studies","degree_name":"Master of Sciences (Engineering)","degree_level":"masters","degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Tyler, Dustin"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2013,"date_issued":"2013-03-08","date_published":"2013-03-08","updated_at":"2026-07-24T03:35:52Z","subjects":["Biomedical Engineering","Neurology","Neurosciences","interfascicular","peripheral nerve","neural recording","source separation"],"languages":["English"],"rights":["unrestricted","This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws."],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Tyler, Dustin"]},{"key":"dc:creator","label":"Author","values":["Kolb, Ilya"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2013-03-08"]},{"key":"dc:publisher","label":"Institution","values":["Case Western Reserve University School of Graduate Studies / OhioLINK"]},{"key":"dc:type","label":"Dc Type","values":["Electronic Thesis or Dissertation"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["masters"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Sciences (Engineering)"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["Case Western Reserve University School of Graduate Studies"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biomedical Engineering","Neurology","Neurosciences","interfascicular","peripheral nerve","neural recording","source separation"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]},{"key":"dc:rights","label":"Dc Rights","values":["unrestricted","This thesis or dissertation is protected by copyright: all rights reserved. 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Directed interfascicular contacts were found to record compound action potentials (CAPs) with a meanSNR (at p = 0.05) of 24.5 dB with respect to interference sources. Contacts that (1)faced opposite directions and (2) were placed in various positions within theepineurium were found to record independent information from the nerve (mixing matrix |det(H)|>0.05 for all electrode configurations). This neuralinformation recorded using interfascicular electrodes may potentially be useful forcommand signal extraction algorithms."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf","p.65","1.3 MB"]},{"key":"dc:title","label":"Title","values":["Characteristics and usefulness of interfascicular contacts in peripheral nerve recording"]}]}],"canonical_facts":{"dc:contributor":["Tyler, Dustin"],"dc:creator":["Kolb, Ilya"],"dc:date":["2013-03-08"],"dc:description":["Neural interfaces have been used in conjunction with source separationalgorithms to address the challenge of extracting useful command signals fromnerves. A peripheral nerve interface is generally useful for signal extraction if it (1) exhibits favorable recording characteristics such as signal-to-noise ratio and (2) provides as many independent channels of neural information as possible. We investigated the usefulness of novel interfascicular electrodes in acute experiments on the rabbit sciatic nerve (n = 4). Directed interfascicular contacts were found to record compound action potentials (CAPs) with a meanSNR (at p = 0.05) of 24.5 dB with respect to interference sources. Contacts that (1)faced opposite directions and (2) were placed in various positions within theepineurium were found to record independent information from the nerve (mixing matrix |det(H)|>0.05 for all electrode configurations). This neuralinformation recorded using interfascicular electrodes may potentially be useful forcommand signal extraction algorithms."],"dc:format":["application/pdf","p.65","1.3 MB"],"dc:identifier":["http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212"],"dc:language":["English"],"dc:publisher":["Case Western Reserve University School of Graduate Studies / OhioLINK"],"dc:rights":["unrestricted","This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws."],"dc:subject":["Biomedical Engineering","Neurology","Neurosciences","interfascicular","peripheral nerve","neural recording","source separation"],"dc:title":["Characteristics and usefulness of interfascicular contacts in peripheral nerve recording"],"dc:type":["Electronic Thesis or Dissertation"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_level":["masters"],"thesis:degree_name":["Master of Sciences (Engineering)"],"thesis:institution_name":["Case Western Reserve University School of Graduate Studies"]},"updated_at":"2026-07-24T03:35:52Z"}