{"id":{"repo_id":"nus","oai_identifier":"oai:scholarbank.nus.edu.sg:10635/37582"},"canonical_url":"https://search.dev.ndltd.org/etd/nus/oai:scholarbank.nus.edu.sg:10635/37582","repository":{"repo_id":"nus","name":"National University of Singapore","base_url":"https://scholarbank.nus.edu.sg/oai/request"},"display":{"title":"Survival of breast cancer patients and the potential for better prognostication","abstract":"Many factors influence the survival of patients with breast cancer. Tumour biology is likely the most important; secondly, the treatment options and the response to the treatment. Individuals with the same stage and similar pathological diagnoses can experience different clinical courses. Patient factors including ethnicity affect tumour biology, treatment and its response. There are prognostic tools using clinical and tumour indicators, but most are not individualised. Molecular platforms for personalised medicine has since evolved and perhaps will provide better prognostication. In this thesis, we study the ethnic difference in survival between an Asian and a Western population: Singapore and Stockholm; survival between different ethnic groups in Singapore: Chinese, Malays and Indians; the effects of biological factors of tumours on survival amongst the different ethnic groups in Singapore; and the use of a custom molecular array as a potential for better prognostication in addition to standard clinical tests in Singaporean women.","abstract_html":"Many factors influence the survival of patients with breast cancer. Tumour biology is likely the most important; secondly, the treatment options and the response to the treatment. Individuals with the same stage and similar pathological diagnoses can experience different clinical courses. Patient factors including ethnicity affect tumour biology, treatment and its response. There are prognostic tools using clinical and tumour indicators, but most are not individualised. Molecular platforms for personalised medicine has since evolved and perhaps will provide better prognostication. In this thesis, we study the ethnic difference in survival between an Asian and a Western population: Singapore and Stockholm; survival between different ethnic groups in Singapore: Chinese, Malays and Indians; the effects of biological factors of tumours on survival amongst the different ethnic groups in Singapore; and the use of a custom molecular array as a potential for better prognostication in addition to standard clinical tests in Singaporean women.","abstract_has_math":false,"creators":["TAN KIAT TEE, BENITA"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["CHIA KEE SENG"],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012-07-26","date_published":"2012-07-26","updated_at":"2026-08-21T16:47:09Z","subjects":["breast cancer, survival, ethnicity, tumour biology, receptor status, molecular signature"],"languages":["en"],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://scholarbank.nus.edu.sg/handle/10635/37582","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"source_record":{"url":"https://scholarbank.nus.edu.sg/oai/request?verb=GetRecord&metadataPrefix=dim&identifier=oai%3Ascholarbank.nus.edu.sg%3A10635%2F37582","prefix":"dim"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH"]},{"key":"dc:contributor.supervisor","label":"Supervisor","values":["CHIA KEE SENG"]},{"key":"dc:creator","label":"Author","values":["TAN KIAT TEE, BENITA"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2013-04-30T18:01:31Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2013-04-30T18:01:31Z"]},{"key":"dc:date.issued","label":"Date","values":["2012-07-26"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["http://scholarbank.nus.edu.sg/handle/10635/37582"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["breast cancer, survival, ethnicity, tumour biology, receptor status, molecular signature"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["en"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://scholarbank.nus.edu.sg/bitstreams/e026ec74-b7ca-45f8-90a7-a650eae7bfc5/download","http://scholarbank.nus.edu.sg/handle/10635/37582"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Many factors influence the survival of patients with breast cancer. 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In this thesis, we study the ethnic difference in survival between an Asian and a Western population: Singapore and Stockholm; survival between different ethnic groups in Singapore: Chinese, Malays and Indians; the effects of biological factors of tumours on survival amongst the different ethnic groups in Singapore; and the use of a custom molecular array as a potential for better prognostication in addition to standard clinical tests in Singaporean women."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["Ph.D"]},{"key":"dc:format.checksum.md5","label":"Dc Format Checksum Md5","values":["a561c747cc15c0b929588e27c21cf3c1","1f5abce09a75f6525be96098de0f61c4"]},{"key":"dc:title","label":"Title","values":["Survival of breast cancer patients and the potential for better prognostication"]}]}],"canonical_facts":{"dc:contributor.other":["SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH"],"dc:contributor.supervisor":["CHIA KEE SENG"],"dc:creator":["TAN KIAT TEE, BENITA"],"dc:date.accessioned":["2013-04-30T18:01:31Z"],"dc:date.available":["2013-04-30T18:01:31Z"],"dc:date.issued":["2012-07-26"],"dc:description.abstract":["Many factors influence the survival of patients with breast cancer. Tumour biology is likely the most important; secondly, the treatment options and the response to the treatment. Individuals with the same stage and similar pathological diagnoses can experience different clinical courses. Patient factors including ethnicity affect tumour biology, treatment and its response. There are prognostic tools using clinical and tumour indicators, but most are not individualised. Molecular platforms for personalised medicine has since evolved and perhaps will provide better prognostication. In this thesis, we study the ethnic difference in survival between an Asian and a Western population: Singapore and Stockholm; survival between different ethnic groups in Singapore: Chinese, Malays and Indians; the effects of biological factors of tumours on survival amongst the different ethnic groups in Singapore; and the use of a custom molecular array as a potential for better prognostication in addition to standard clinical tests in Singaporean women."],"dc:description.degree":["Ph.D"],"dc:format.checksum.md5":["a561c747cc15c0b929588e27c21cf3c1","1f5abce09a75f6525be96098de0f61c4"],"dc:identifier.uri":["https://scholarbank.nus.edu.sg/bitstreams/e026ec74-b7ca-45f8-90a7-a650eae7bfc5/download","http://scholarbank.nus.edu.sg/handle/10635/37582"],"dc:language.iso":["en"],"dc:relation.isreferencedby":["http://scholarbank.nus.edu.sg/handle/10635/37582"],"dc:subject":["breast cancer, survival, ethnicity, tumour biology, receptor status, molecular signature"],"dc:title":["Survival of breast cancer patients and the potential for better prognostication"],"dc:type":["Thesis"]},"updated_at":"2026-08-21T16:47:09Z"}