{"id":{"repo_id":"nus","oai_identifier":"oai:scholarbank.nus.edu.sg:10635/34493"},"canonical_url":"https://search.dev.ndltd.org/etd/nus/oai:scholarbank.nus.edu.sg:10635/34493","repository":{"repo_id":"nus","name":"National University of Singapore","base_url":"https://scholarbank.nus.edu.sg/oai/request"},"display":{"title":"ONTOGENESIS OF MURINE NEURAL CREST DERIVATIVES","abstract":"The neural crest is an epithelial domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to mesectoderm. However the origin of mesectoderm has not been unequivocally proven. Furthermore the issue of whether neural crest cells are pluripotent or fate restricted has also been controversial. In the current study we try to address the issue of whether cell fate and origin are linked in the neural crest and propose that there are two populations of delaminating cells with distinct cell fates.","abstract_html":"The neural crest is an epithelial domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to mesectoderm. However the origin of mesectoderm has not been unequivocally proven. Furthermore the issue of whether neural crest cells are pluripotent or fate restricted has also been controversial. In the current study we try to address the issue of whether cell fate and origin are linked in the neural crest and propose that there are two populations of delaminating cells with distinct cell fates.","abstract_has_math":false,"creators":["LEE TECK HO, RAYMOND"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-11-28","date_published":"2011-11-28","updated_at":"2026-07-24T03:31:38Z","subjects":["Neural Crest, Ectomesenchyme"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["LEE TECK HO, RAYMOND"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2011-11-28"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://scholarbank.nus.edu.sg/handle/10635/34493"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Neural Crest, Ectomesenchyme"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://scholarbank.nus.edu.sg/bitstreams/c1925518-bd46-4f4b-8b0c-89561bcb5761/download"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The neural crest is an epithelial domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to mesectoderm. However the origin of mesectoderm has not been unequivocally proven. Furthermore the issue of whether neural crest cells are pluripotent or fate restricted has also been controversial. In the current study we try to address the issue of whether cell fate and origin are linked in the neural crest and propose that there are two populations of delaminating cells with distinct cell fates."]},{"key":"dc:format.checksum.md5","label":"Dc Format Checksum Md5","values":["5b15e311adc6e5f3148a83cab8dd8480","4c0fe7ba907190b4889f9aa2291689b9"]},{"key":"dc:title","label":"Title","values":["ONTOGENESIS OF MURINE NEURAL CREST DERIVATIVES"]}]}],"canonical_facts":{"dc:creator":["LEE TECK HO, RAYMOND"],"dc:date.issued":["2011-11-28"],"dc:description.abstract":["The neural crest is an epithelial domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to mesectoderm. However the origin of mesectoderm has not been unequivocally proven. Furthermore the issue of whether neural crest cells are pluripotent or fate restricted has also been controversial. In the current study we try to address the issue of whether cell fate and origin are linked in the neural crest and propose that there are two populations of delaminating cells with distinct cell fates."],"dc:format.checksum.md5":["5b15e311adc6e5f3148a83cab8dd8480","4c0fe7ba907190b4889f9aa2291689b9"],"dc:identifier.uri":["https://scholarbank.nus.edu.sg/bitstreams/c1925518-bd46-4f4b-8b0c-89561bcb5761/download"],"dc:relation.isreferencedby":["https://scholarbank.nus.edu.sg/handle/10635/34493"],"dc:subject":["Neural Crest, Ectomesenchyme"],"dc:title":["ONTOGENESIS OF MURINE NEURAL CREST DERIVATIVES"],"dc:type":["Thesis"]},"updated_at":"2026-07-24T03:31:38Z"}