RECYCLING OF WASTE BLOOD INTO FUNCTIONAL CARBON NANOPARTICLES

This thesis presents an innovative approach to recycling blood waste by converting expired blood into hemoglobin-derived carbon nanoparticles (Hemodots, HDs) with potential biomedical applications. The study addresses challenges in blood waste management and explores alternative anticoagulant therapies. Through a hydrothermal process, optimal conditions for HD synthesis were identified at 230°C for 10 minutes, maximizing fluorescence intensity and carbon nanoparticle quality. Characterization confirmed HDs’ carbon-based structure, nitrogen-doping, and size distribution (average diameter of 8 nm), with properties resembling commercial carbon dots. In vitro tests demonstrated HDs’ dose-dependent anticoagulant effects, reducing clot formation with minimal impact on blood viscosity and low toxicity, indicating high biocompatibility. This work highlights the feasibility of transforming blood waste into valuable nanomaterials, proposing a sustainable solution for waste management and contributing to advanced anticoagulant alternatives for biomedical applications.

Author dc:creator

• SONG YUJIN

• Anticoagulant Therapy
• Sustainable Nanotechnology
• Blood Waste Recycling
• Fluorescent Nanoparticles
• Carbon Dots
• Carbon Nanoparticles

Licence

• https://scholarbank.nus.edu.sg/bitstreams/7ce3dccf-3f27-490e-9818-71b80216f9af/download