{"id":{"repo_id":"nus","oai_identifier":"oai:scholarbank.nus.edu.sg:10635/239118"},"canonical_url":"https://search.dev.ndltd.org/etd/nus/oai:scholarbank.nus.edu.sg:10635/239118","repository":{"repo_id":"nus","name":"National University of Singapore","base_url":"https://scholarbank.nus.edu.sg/oai/request"},"display":{"title":"THE CONSTRUCTION OF NAPHTHOTUBES AND THEIR APPLICATIONS IN MOLECULAR RECOGNITION, ENANTIOSELECTIVE RECOGNITION AND CHARGE TRANSFER","abstract":"The molecular recognition of macrocyclic hosts plays a critical role in their functions in supramolecular chemistry and biological systems. However, the understanding of molecular recognition remains limited. Herein, a series of new macrocyclic hosts (naphthotubes) with the deep hydrophobic cavity, polar sites inside the cavity, and good water-solubility have been designed and synthesized. Firstly, the exceptional binding properties and optical tuning abilities of amide naphthotubes with a series of fluorescent dyes were systematically discussed. Secondly, a new pair of water-soluble chiral naphthotubes with enantioselective recognition ability were synthesized and their chiral recognition abilities were thoroughly studied. Lastly, two new amine naphthotubes were prepared through a post-modification strategy, and their properties in molecular recognition and electron transfer were explored. We hope that the findings from this research will contribute to a better understanding of molecular recognition and open new avenues for the development of macrocyclic hosts in various fields.","abstract_html":"The molecular recognition of macrocyclic hosts plays a critical role in their functions in supramolecular chemistry and biological systems. However, the understanding of molecular recognition remains limited. Herein, a series of new macrocyclic hosts (naphthotubes) with the deep hydrophobic cavity, polar sites inside the cavity, and good water-solubility have been designed and synthesized. Firstly, the exceptional binding properties and optical tuning abilities of amide naphthotubes with a series of fluorescent dyes were systematically discussed. Secondly, a new pair of water-soluble chiral naphthotubes with enantioselective recognition ability were synthesized and their chiral recognition abilities were thoroughly studied. Lastly, two new amine naphthotubes were prepared through a post-modification strategy, and their properties in molecular recognition and electron transfer were explored. We hope that the findings from this research will contribute to a better understanding of molecular recognition and open new avenues for the development of macrocyclic hosts in various fields.","abstract_has_math":false,"creators":["CHEN ZHAO"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2022,"date_issued":"2022-08-19","date_published":"2022-08-19","updated_at":"2026-07-24T03:32:56Z","subjects":["macrocyclic host","enantioselective recognition","supramolecular","molecualr recognition"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":null,"outbound_label":null,"outbound_source":null},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["CHEN ZHAO"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.issued","label":"Date","values":["2022-08-19"]},{"key":"dc:relation.isreferencedby","label":"Dc Relation Isreferencedby","values":["https://scholarbank.nus.edu.sg/handle/10635/239118"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["macrocyclic host","enantioselective recognition","supramolecular","molecualr recognition"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://scholarbank.nus.edu.sg/bitstreams/0151efa9-eabf-4138-9c47-d2efe537e308/download","https://scholarbank.nus.edu.sg/bitstreams/c9106a01-6e2d-42bd-8a81-825ffbf7dfc0/download"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The molecular recognition of macrocyclic hosts plays a critical role in their functions in supramolecular chemistry and biological systems. However, the understanding of molecular recognition remains limited. Herein, a series of new macrocyclic hosts (naphthotubes) with the deep hydrophobic cavity, polar sites inside the cavity, and good water-solubility have been designed and synthesized. Firstly, the exceptional binding properties and optical tuning abilities of amide naphthotubes with a series of fluorescent dyes were systematically discussed. Secondly, a new pair of water-soluble chiral naphthotubes with enantioselective recognition ability were synthesized and their chiral recognition abilities were thoroughly studied. Lastly, two new amine naphthotubes were prepared through a post-modification strategy, and their properties in molecular recognition and electron transfer were explored. We hope that the findings from this research will contribute to a better understanding of molecular recognition and open new avenues for the development of macrocyclic hosts in various fields."]},{"key":"dc:format.checksum.md5","label":"Dc Format Checksum Md5","values":["c7a3deb87348d392f554f6c5eec8ad1b","f3a3bcf24779d60e2d62fcea134f210f","64389b60642413036bafed66b4e0b72f","6b0de5588e6c2931bb8796f23eb99ff0"]},{"key":"dc:title","label":"Title","values":["THE CONSTRUCTION OF NAPHTHOTUBES AND THEIR APPLICATIONS IN MOLECULAR RECOGNITION, ENANTIOSELECTIVE RECOGNITION AND CHARGE TRANSFER"]}]}],"canonical_facts":{"dc:creator":["CHEN ZHAO"],"dc:date.issued":["2022-08-19"],"dc:description.abstract":["The molecular recognition of macrocyclic hosts plays a critical role in their functions in supramolecular chemistry and biological systems. However, the understanding of molecular recognition remains limited. Herein, a series of new macrocyclic hosts (naphthotubes) with the deep hydrophobic cavity, polar sites inside the cavity, and good water-solubility have been designed and synthesized. Firstly, the exceptional binding properties and optical tuning abilities of amide naphthotubes with a series of fluorescent dyes were systematically discussed. Secondly, a new pair of water-soluble chiral naphthotubes with enantioselective recognition ability were synthesized and their chiral recognition abilities were thoroughly studied. Lastly, two new amine naphthotubes were prepared through a post-modification strategy, and their properties in molecular recognition and electron transfer were explored. 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