{"id":{"repo_id":"nus","oai_identifier":"oai:scholarbank.nus.edu.sg:10635/15522"},"canonical_url":"https://search.dev.ndltd.org/etd/nus/oai:scholarbank.nus.edu.sg:10635/15522","repository":{"repo_id":"nus","name":"National University of Singapore","base_url":"https://scholarbank.nus.edu.sg/oai/request"},"display":{"title":"Characterization of human adipose tissue-derived adult multipotent precursor cells","abstract":"Recent literature has proposed the existence of a putative subpopulations of stem cells in the adipose tissue stroma. These adipose derived stem cells (ADSCs) under certain conditions express characteristics of various mesenchymal lineages. This thesis showed that 1,25a??dihydroxyvitamin D3 worked synergistically with I?-glycerophosphate and ascorbic acid to induce ADSCs towards the osteogenic lineage. In two- and three-dimensional induction studies, ADSC were able to express bone characteristics which were then confirmed in an in vivo model. 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