Certain disorders, like attention deficit hyperactive disorder (ADHD), are challenging to diagnose, particularly via clinical assessment, as the standard diagnostic criteria and testing methods vary among clinicians. ADHD is commonly known as a neurodevelopmental disorder, and as such, certain genetic components may potentially aid in the diagnostic process. Previous and current literature has identified ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3) as a highly probable genetic component underlying ADHD. This study will primarily investigate the ST3GAL3 gene mutation within a specific single nucleotide polymorphism (SNP) that may be playing a role in the development of ADHD, along with anxiety and depression, as these two disorders are commonly diagnosed alongside ADHD. Loop-mediated isothermal amplification (LAMP) will be the primary assay utilized in this study.
","abstract_html":"<p>Certain disorders, like attention deficit hyperactive disorder (ADHD), are challenging to diagnose, particularly via clinical assessment, as the standard diagnostic criteria and testing methods vary among clinicians. ADHD is commonly known as a neurodevelopmental disorder, and as such, certain genetic components may potentially aid in the diagnostic process. Previous and current literature has identified ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (<em>ST3GAL3</em>) as a highly probable genetic component underlying ADHD. This study will primarily investigate the <em>ST3GAL3</em> gene mutation within a specific single nucleotide polymorphism (SNP) that may be playing a role in the development of ADHD, along with anxiety and depression, as these two disorders are commonly diagnosed alongside ADHD. Loop-mediated isothermal amplification (LAMP) will be the primary assay utilized in this study.</p>","abstract_has_math":false,"creators":["Balinski, Rebecca R"],"institution":null,"degree_name":"Master of Science","degree_level":"Thesis","degree_discipline":"Psychological Science","degree_department":null,"school":null,"contributors":["Dr. Amber LaCrosse"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-04-01T07:00:00Z","date_published":"2025-04-01T07:00:00Z","updated_at":"2026-07-24T03:24:36Z","subjects":["ADHD","Anxiety","Depression","SNP","ST3GAL3 gene","Loop mediated isothermal amplification","Clinical Psychology"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://commons.nmu.edu/theses/877","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Dr. Amber LaCrosse"]},{"key":"dc:creator","label":"Author","values":["Balinski, Rebecca R"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2030-04-01T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Psychological Science"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["ADHD","Anxiety","Depression","SNP","ST3GAL3 gene","Loop mediated isothermal amplification","Clinical Psychology"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://commons.nmu.edu/theses/877"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Certain disorders, like attention deficit hyperactive disorder (ADHD), are challenging to diagnose, particularly via clinical assessment, as the standard diagnostic criteria and testing methods vary among clinicians. ADHD is commonly known as a neurodevelopmental disorder, and as such, certain genetic components may potentially aid in the diagnostic process. Previous and current literature has identified ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3) as a highly probable genetic component underlying ADHD. This study will primarily investigate the ST3GAL3 gene mutation within a specific single nucleotide polymorphism (SNP) that may be playing a role in the development of ADHD, along with anxiety and depression, as these two disorders are commonly diagnosed alongside ADHD. Loop-mediated isothermal amplification (LAMP) will be the primary assay utilized in this study.
"]},{"key":"dc:title","label":"Title","values":["ST3GAL3 GENE MUTATION WITHIN THE SINGULAR NUCLEOTIDE POLYMORPHISM, RS3952787, POTENTIALLY COULD PREDICT ATTENTION DEFICIT HYPERACTIVE DISORDER, ANXIETY, AND DEPRESSION"]}]}],"canonical_facts":{"dc:contributor":["Dr. Amber LaCrosse"],"dc:creator":["Balinski, Rebecca R"],"dc:date.available":["2030-04-01T07:00:00Z"],"dc:description.abstract":["Certain disorders, like attention deficit hyperactive disorder (ADHD), are challenging to diagnose, particularly via clinical assessment, as the standard diagnostic criteria and testing methods vary among clinicians. ADHD is commonly known as a neurodevelopmental disorder, and as such, certain genetic components may potentially aid in the diagnostic process. Previous and current literature has identified ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (ST3GAL3) as a highly probable genetic component underlying ADHD. This study will primarily investigate the ST3GAL3 gene mutation within a specific single nucleotide polymorphism (SNP) that may be playing a role in the development of ADHD, along with anxiety and depression, as these two disorders are commonly diagnosed alongside ADHD. Loop-mediated isothermal amplification (LAMP) will be the primary assay utilized in this study.
"],"dc:identifier":["https://commons.nmu.edu/theses/877"],"dc:subject":["ADHD","Anxiety","Depression","SNP","ST3GAL3 gene","Loop mediated isothermal amplification","Clinical Psychology"],"dc:title":["ST3GAL3 GENE MUTATION WITHIN THE SINGULAR NUCLEOTIDE POLYMORPHISM, RS3952787, POTENTIALLY COULD PREDICT ATTENTION DEFICIT HYPERACTIVE DISORDER, ANXIETY, AND DEPRESSION"],"thesis:degree_discipline":["Psychological Science"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science"]},"updated_at":"2026-07-24T03:24:36Z"}