{"id":{"repo_id":"njit","oai_identifier":"oai:digitalcommons.njit.edu:theses-1571"},"canonical_url":"https://search.dev.ndltd.org/etd/njit/oai:digitalcommons.njit.edu:theses-1571","repository":{"repo_id":"njit","name":"NJIT","base_url":"https://digitalcommons.njit.edu/do/oai/"},"display":{"title":"Spinning of collagen fibers and characterizing thermal, mechanical, tensile and structural properties","abstract":"Collagen is the most important building block in the entire animal world. It plays an important role in regeneration of broken bones and wound healing, also helps grow blood vessels to feed the healing areas. The use of synthetic materials has been extensive, but these materials have there own limits and drawbacks. Poor biocompatibility of these materials is the main issue and often result in inflammations. Hence collagen is being heralded as one of the most appropriate replacement as an implantable material. The reasons being that it is a naturally occurring material, exhibits high biocompatibility low antigenicity and host response. This study involes spinning collagen fibers using dispersion made from bovine tendon, and to modify their properties via cross-linking by treating the fibers with gluteraldehdye. These fibers are characterized for mechanical properties, effect of temperature on dimension changes, temperature dependent heat flow, and temperature dependent weight. The above tests are conducted using TMA, DSC and TGA.The fiber diameters and surface features are studied using SEM. The results of these analyses are compared with cross-linking and without cross-linking for each of the three dispersion percentages. The mechanical behavior of cross linked collagen fibers was enhanced relative to the non cross linked fibers with higher denaturation temperature and lower tensile deformation.","abstract_html":"Collagen is the most important building block in the entire animal world. It plays an important role in regeneration of broken bones and wound healing, also helps grow blood vessels to feed the healing areas. The use of synthetic materials has been extensive, but these materials have there own limits and drawbacks. Poor biocompatibility of these materials is the main issue and often result in inflammations. Hence collagen is being heralded as one of the most appropriate replacement as an implantable material. The reasons being that it is a naturally occurring material, exhibits high biocompatibility low antigenicity and host response. This study involes spinning collagen fibers using dispersion made from bovine tendon, and to modify their properties via cross-linking by treating the fibers with gluteraldehdye. These fibers are characterized for mechanical properties, effect of temperature on dimension changes, temperature dependent heat flow, and temperature dependent weight. The above tests are conducted using TMA, DSC and TGA.The fiber diameters and surface features are studied using SEM. The results of these analyses are compared with cross-linking and without cross-linking for each of the three dispersion percentages. The mechanical behavior of cross linked collagen fibers was enhanced relative to the non cross linked fibers with higher denaturation temperature and lower tensile deformation.","abstract_has_math":false,"creators":["Tatagiri, Grace Evangelin"],"institution":null,"degree_name":"Master of Science in Biomedical Engineering - (M.S.)","degree_level":null,"degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Michael Jaffe","Treena Livingston Arinzeh","George Collins"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2004,"date_issued":"2004-05-31T07:00:00Z","date_published":"2004-05-31T07:00:00Z","updated_at":"2026-07-24T03:23:27Z","subjects":["Spinning collagen fibers","Dispersion","Bovine tendon","Biomedical Engineering and Bioengineering"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.njit.edu/theses/572","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Michael Jaffe","Treena Livingston Arinzeh","George Collins"]},{"key":"dc:creator","label":"Author","values":["Tatagiri, Grace Evangelin"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Biomedical Engineering - (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Spinning collagen fibers","Dispersion","Bovine tendon","Biomedical Engineering and Bioengineering"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.njit.edu/theses/572"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Collagen is the most important building block in the entire animal world. It plays an important role in regeneration of broken bones and wound healing, also helps grow blood vessels to feed the healing areas. The use of synthetic materials has been extensive, but these materials have there own limits and drawbacks. Poor biocompatibility of these materials is the main issue and often result in inflammations. Hence collagen is being heralded as one of the most appropriate replacement as an implantable material. The reasons being that it is a naturally occurring material, exhibits high biocompatibility low antigenicity and host response. This study involes spinning collagen fibers using dispersion made from bovine tendon, and to modify their properties via cross-linking by treating the fibers with gluteraldehdye. These fibers are characterized for mechanical properties, effect of temperature on dimension changes, temperature dependent heat flow, and temperature dependent weight. The above tests are conducted using TMA, DSC and TGA.The fiber diameters and surface features are studied using SEM. The results of these analyses are compared with cross-linking and without cross-linking for each of the three dispersion percentages. The mechanical behavior of cross linked collagen fibers was enhanced relative to the non cross linked fibers with higher denaturation temperature and lower tensile deformation."]},{"key":"dc:title","label":"Title","values":["Spinning of collagen fibers and characterizing thermal, mechanical, tensile and structural properties"]}]}],"canonical_facts":{"dc:contributor":["Michael Jaffe","Treena Livingston Arinzeh","George Collins"],"dc:creator":["Tatagiri, Grace Evangelin"],"dc:description.abstract":["Collagen is the most important building block in the entire animal world. It plays an important role in regeneration of broken bones and wound healing, also helps grow blood vessels to feed the healing areas. The use of synthetic materials has been extensive, but these materials have there own limits and drawbacks. Poor biocompatibility of these materials is the main issue and often result in inflammations. Hence collagen is being heralded as one of the most appropriate replacement as an implantable material. The reasons being that it is a naturally occurring material, exhibits high biocompatibility low antigenicity and host response. This study involes spinning collagen fibers using dispersion made from bovine tendon, and to modify their properties via cross-linking by treating the fibers with gluteraldehdye. These fibers are characterized for mechanical properties, effect of temperature on dimension changes, temperature dependent heat flow, and temperature dependent weight. The above tests are conducted using TMA, DSC and TGA.The fiber diameters and surface features are studied using SEM. The results of these analyses are compared with cross-linking and without cross-linking for each of the three dispersion percentages. The mechanical behavior of cross linked collagen fibers was enhanced relative to the non cross linked fibers with higher denaturation temperature and lower tensile deformation."],"dc:identifier":["https://digitalcommons.njit.edu/theses/572"],"dc:subject":["Spinning collagen fibers","Dispersion","Bovine tendon","Biomedical Engineering and Bioengineering"],"dc:title":["Spinning of collagen fibers and characterizing thermal, mechanical, tensile and structural properties"],"dc:type":["Thesis"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_name":["Master of Science in Biomedical Engineering - (M.S.)"]},"updated_at":"2026-07-24T03:23:27Z"}