SNP auto-calling using artificial neural networks

In recent years feedforward artificial neural networks (ANN) and their training algorithms have become an effective methodology for the construction of nonlinear systems that solve the statistical problem of classification. The ability of ANNs to solve this problem is highly germane to making progress in the refinement of DNA microarray analysis and techniques regarding this issue. This study attempts to deal with the classification of microarray data and the comparison and validation of simple feedforward ANNs in partitioning high dimensional data. In doing this the efficacy of using ANNs as a genotyping tool will be proven. Furthermore, it has been determined through extensive testing that the classification abilities of simple feedforward ANNs are at least comparable with that of SVMs.

Name thesis:degree_name

Master of Science in Computer Science - (M.S.)

Discipline thesis:degree_discipline

Computer Science

Year

2005

Author dc:creator

• Spivak, Damien

Contributors dc:contributor

• Qun Ma
• Frank Y. Shih
• Barry Cohen

• Nonlinear systems
• DNA microarray analysis
• Artificial neural networks
• Computer Sciences

Repository record dc:identifier

https://digitalcommons.njit.edu/theses/510

OAI identifier oai:identifier

oai:digitalcommons.njit.edu:theses-1509