Continuum mechanical analysis of space and time dependent deformation pattern of brain with blunt injury

Deformation of human brain due to acceleration impact has been widely accepted as the direct connection to the Trauma Brain Injury (TBI). However, the limitation of obtaining deformation data of TBI is a major obstacle to understanding TBI mechanism. This experiment mainly focuses on developing a method to measure deformation pattern of brain with blunt injury. First of all, displacement data of markers on sagittal plane of an injury head model was collected using 3D reconstruction software after an impact test. Second, the displacement data was used to calculate 2D Lagrangian strain tensor and the principal strain. The temporal and spatial results of principal strain under different variables including impact velocity (5 mile/hour, 3 mile/ hour), impact location (crown head, front head) and concentration of gel used to build the brain model (10%, 20%) were compared. The results shown larger strain values within the variables of higher impact velocity, crown head impact location and 10% gel. The spatial location results shown clearly the difference in terms of deformation pattern of different impact locations.

Name thesis:degree_name

Master of Science in Biomedical Engineering - (M.S.)

Discipline thesis:degree_discipline

Biomedical Engineering

Year

2016

Author dc:creator

• Miao, Chen

Contributors dc:contributor

• Bryan J. Pfister
• N. Chandra
• Max Roman

• Human brain deformation
• Traumatic brain iunjury
• Acceleration impact
• Biomedical Engineering and Bioengineering

Repository record dc:identifier

https://digitalcommons.njit.edu/theses/286

OAI identifier oai:identifier

oai:digitalcommons.njit.edu:theses-1285