{"id":{"repo_id":"njit","oai_identifier":"oai:digitalcommons.njit.edu:theses-1138"},"canonical_url":"https://search.dev.ndltd.org/etd/njit/oai:digitalcommons.njit.edu:theses-1138","repository":{"repo_id":"njit","name":"NJIT","base_url":"https://digitalcommons.njit.edu/do/oai/"},"display":{"title":"Experimental evaluation of near infrared light penetration into neural tissue","abstract":"Near infrared (NIR) lasers find applications in medicine both for diagnostic and treatment purposes. Penetration depth into the tissue is a critical parameter to be considered in these NIR laser applications. Published data on the optical properties of rodent neural tissue are rare, despite the frequent use of rats as animal models. The aim of this study was to directly measure the light intensity profile inside the rat brain gray matter that is illuminated by an NIR laser beam. The local light intensities were sampled using an optical fiber inserted into the brain. The intensity profile in the axial direction to the laser beam had an initial fast decreasing phase followed by a less steeper slope by distance. In general, the light penetrated several times farther in the direction of the beam than its spread in the radial direction.","abstract_html":"Near infrared (NIR) lasers find applications in medicine both for diagnostic and treatment purposes. Penetration depth into the tissue is a critical parameter to be considered in these NIR laser applications. Published data on the optical properties of rodent neural tissue are rare, despite the frequent use of rats as animal models. The aim of this study was to directly measure the light intensity profile inside the rat brain gray matter that is illuminated by an NIR laser beam. The local light intensities were sampled using an optical fiber inserted into the brain. The intensity profile in the axial direction to the laser beam had an initial fast decreasing phase followed by a less steeper slope by distance. In general, the light penetrated several times farther in the direction of the beam than its spread in the radial direction.","abstract_has_math":false,"creators":["Parikh, Ujwal Anil"],"institution":null,"degree_name":"Master of Science in Biomedical Engineering - (M.S.)","degree_level":null,"degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Mesut Sahin","Sergei Adamovich","Bryan J. Pfister"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012-05-31T07:00:00Z","date_published":"2012-05-31T07:00:00Z","updated_at":"2026-07-24T03:22:26Z","subjects":["Near infrared lasers","Light intensity profile","Biomedical Engineering and Bioengineering"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.njit.edu/theses/139","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Mesut Sahin","Sergei Adamovich","Bryan J. Pfister"]},{"key":"dc:creator","label":"Author","values":["Parikh, Ujwal Anil"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Biomedical Engineering - (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Near infrared lasers","Light intensity profile","Biomedical Engineering and Bioengineering"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.njit.edu/theses/139"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Near infrared (NIR) lasers find applications in medicine both for diagnostic and treatment purposes. Penetration depth into the tissue is a critical parameter to be considered in these NIR laser applications. Published data on the optical properties of rodent neural tissue are rare, despite the frequent use of rats as animal models. The aim of this study was to directly measure the light intensity profile inside the rat brain gray matter that is illuminated by an NIR laser beam. The local light intensities were sampled using an optical fiber inserted into the brain. The intensity profile in the axial direction to the laser beam had an initial fast decreasing phase followed by a less steeper slope by distance. In general, the light penetrated several times farther in the direction of the beam than its spread in the radial direction."]},{"key":"dc:title","label":"Title","values":["Experimental evaluation of near infrared light penetration into neural tissue"]}]}],"canonical_facts":{"dc:contributor":["Mesut Sahin","Sergei Adamovich","Bryan J. Pfister"],"dc:creator":["Parikh, Ujwal Anil"],"dc:description.abstract":["Near infrared (NIR) lasers find applications in medicine both for diagnostic and treatment purposes. Penetration depth into the tissue is a critical parameter to be considered in these NIR laser applications. Published data on the optical properties of rodent neural tissue are rare, despite the frequent use of rats as animal models. The aim of this study was to directly measure the light intensity profile inside the rat brain gray matter that is illuminated by an NIR laser beam. The local light intensities were sampled using an optical fiber inserted into the brain. The intensity profile in the axial direction to the laser beam had an initial fast decreasing phase followed by a less steeper slope by distance. In general, the light penetrated several times farther in the direction of the beam than its spread in the radial direction."],"dc:identifier":["https://digitalcommons.njit.edu/theses/139"],"dc:subject":["Near infrared lasers","Light intensity profile","Biomedical Engineering and Bioengineering"],"dc:title":["Experimental evaluation of near infrared light penetration into neural tissue"],"dc:type":["Thesis"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_name":["Master of Science in Biomedical Engineering - (M.S.)"]},"updated_at":"2026-07-24T03:22:26Z"}