{"id":{"repo_id":"njit","oai_identifier":"oai:digitalcommons.njit.edu:theses-1116"},"canonical_url":"https://search.dev.ndltd.org/etd/njit/oai:digitalcommons.njit.edu:theses-1116","repository":{"repo_id":"njit","name":"NJIT","base_url":"https://digitalcommons.njit.edu/do/oai/"},"display":{"title":"Soy protein-poly (l-lactic acid) blend nanofibers for drug delivery of nardostachys jatamansi","abstract":"Electrospun nanofibers when nanofi bers are impregnated with drugs play a significant role in drug delivery. Nanomedical approaches to drug delivery focus on developing nanoscale particles or molecules to improve the bioavailab ility of a drug. Biodegradable nanofibers were developed using Poly (L - lactic acid) and Soy protein for the delivery of an ayurvedic drug, Nardostachys jatamansi. A weighed quantity of powdered drug - Nardostachys Jatamansi was subjected to Soxhlet extraction using water and ethanol in equal quantities. Various blends of the drug extract and soy protein solution are prepared and mixed in Poly (L-lactic acid). Nanofibers of Soy Protein - Poly (L-lactic acid) blend along with the drug Nardostachys Jatamansi developed, were morphologically analyzed using Scanning Electron Microscope (SEM) and also for the presence of the drug co ntent with UV spectrometry. This research has opened a new avenue for the drug delivery of Nardostachys jatamansi using nanofibers. However, there are more opportunities to be exploited from the electrospinning of PLLA and the corresponding drug-loaded nanofibers for drug delivery.","abstract_html":"Electrospun nanofibers when nanofi bers are impregnated with drugs play a significant role in drug delivery. Nanomedical approaches to drug delivery focus on developing nanoscale particles or molecules to improve the bioavailab ility of a drug. Biodegradable nanofibers were developed using Poly (L - lactic acid) and Soy protein for the delivery of an ayurvedic drug, Nardostachys jatamansi. A weighed quantity of powdered drug - Nardostachys Jatamansi was subjected to Soxhlet extraction using water and ethanol in equal quantities. Various blends of the drug extract and soy protein solution are prepared and mixed in Poly (L-lactic acid). Nanofibers of Soy Protein - Poly (L-lactic acid) blend along with the drug Nardostachys Jatamansi developed, were morphologically analyzed using Scanning Electron Microscope (SEM) and also for the presence of the drug co ntent with UV spectrometry. This research has opened a new avenue for the drug delivery of Nardostachys jatamansi using nanofibers. However, there are more opportunities to be exploited from the electrospinning of PLLA and the corresponding drug-loaded nanofibers for drug delivery.","abstract_has_math":false,"creators":["Tiwari, Swetha"],"institution":null,"degree_name":"Master of Science in Biomedical Engineering - (M.S.)","degree_level":null,"degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Michael Jaffe","Cheul H. Cho","Treena Livingston Arinzeh"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012-01-31T08:00:00Z","date_published":"2012-01-31T08:00:00Z","updated_at":"2026-07-24T03:22:26Z","subjects":["Nanomedical drug delivery","Biodegradable nanofibers","Biomedical Engineering and Bioengineering"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.njit.edu/theses/117","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Michael Jaffe","Cheul H. Cho","Treena Livingston Arinzeh"]},{"key":"dc:creator","label":"Author","values":["Tiwari, Swetha"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:type","label":"Dc Type","values":["Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science in Biomedical Engineering - (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Nanomedical drug delivery","Biodegradable nanofibers","Biomedical Engineering and Bioengineering"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.njit.edu/theses/117"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Electrospun nanofibers when nanofi bers are impregnated with drugs play a significant role in drug delivery. Nanomedical approaches to drug delivery focus on developing nanoscale particles or molecules to improve the bioavailab ility of a drug. Biodegradable nanofibers were developed using Poly (L - lactic acid) and Soy protein for the delivery of an ayurvedic drug, Nardostachys jatamansi. A weighed quantity of powdered drug - Nardostachys Jatamansi was subjected to Soxhlet extraction using water and ethanol in equal quantities. Various blends of the drug extract and soy protein solution are prepared and mixed in Poly (L-lactic acid). Nanofibers of Soy Protein - Poly (L-lactic acid) blend along with the drug Nardostachys Jatamansi developed, were morphologically analyzed using Scanning Electron Microscope (SEM) and also for the presence of the drug co ntent with UV spectrometry. This research has opened a new avenue for the drug delivery of Nardostachys jatamansi using nanofibers. However, there are more opportunities to be exploited from the electrospinning of PLLA and the corresponding drug-loaded nanofibers for drug delivery."]},{"key":"dc:title","label":"Title","values":["Soy protein-poly (l-lactic acid) blend nanofibers for drug delivery of nardostachys jatamansi"]}]}],"canonical_facts":{"dc:contributor":["Michael Jaffe","Cheul H. Cho","Treena Livingston Arinzeh"],"dc:creator":["Tiwari, Swetha"],"dc:description.abstract":["Electrospun nanofibers when nanofi bers are impregnated with drugs play a significant role in drug delivery. Nanomedical approaches to drug delivery focus on developing nanoscale particles or molecules to improve the bioavailab ility of a drug. Biodegradable nanofibers were developed using Poly (L - lactic acid) and Soy protein for the delivery of an ayurvedic drug, Nardostachys jatamansi. A weighed quantity of powdered drug - Nardostachys Jatamansi was subjected to Soxhlet extraction using water and ethanol in equal quantities. Various blends of the drug extract and soy protein solution are prepared and mixed in Poly (L-lactic acid). Nanofibers of Soy Protein - Poly (L-lactic acid) blend along with the drug Nardostachys Jatamansi developed, were morphologically analyzed using Scanning Electron Microscope (SEM) and also for the presence of the drug co ntent with UV spectrometry. This research has opened a new avenue for the drug delivery of Nardostachys jatamansi using nanofibers. However, there are more opportunities to be exploited from the electrospinning of PLLA and the corresponding drug-loaded nanofibers for drug delivery."],"dc:identifier":["https://digitalcommons.njit.edu/theses/117"],"dc:subject":["Nanomedical drug delivery","Biodegradable nanofibers","Biomedical Engineering and Bioengineering"],"dc:title":["Soy protein-poly (l-lactic acid) blend nanofibers for drug delivery of nardostachys jatamansi"],"dc:type":["Thesis"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_name":["Master of Science in Biomedical Engineering - (M.S.)"]},"updated_at":"2026-07-24T03:22:26Z"}