The modeling and analysis of the electroosmotic flow, diffusion, electrophoretic migration, and adsorption mechanisms of charged and uncharged adsorbates in capillary electrochromatography systems employing charged adsorbent particles - comparisons between theory and experiments

<p>"In this work, the dynamic and equilibrium effects of the presence of an electrical double layer on the electrically-driven mass transport mechanisms of electroosmotic flow (EOF) and electrophoretic migration, as well as the interplay of these transport mechanisms with the diffusion and adsorption mechanisms of charged and uncharged solutes in charged chromatographic media employed in capillary electrochromatography (CEC) and ion exchange systems are modeled, studied, and analyzed. The modelling of these mechanisms has put the analysis of the dynamic behavior of CEC systems to now be based on fundamental scientific understanding and, thus, the design and operation of CEC systems can now be made through engineering science. Furthermore, the modelling of these mechanisms has revolutionized our fundamental understanding of ion-exchange chromatography. For the first time it has been shown how the evolving dynamic behavior of the charge density of a solid adsorptive surface immersed in an electrolytic solution, through the electrical double layer, affects both the transport in the liquid solution and the adsorption rate of charged analytes onto the charged solid surface, and could be responsible for the generation of concentration rings in charged porous adsorbent particles, as experimentally observed by confocal scanning laser microscopy. Finally, theoretical results for the velocity of the EOF and the height equivalent of a theoretical plate (HETP) in CEC systems have been compared with experimental data and the agreement between theory and experiment is found to be good"--Abstract, page iv.</p>

Name thesis:degree_name

Ph. D. in Chemical Engineering

Grantor

University of Missouri--Rolla

Year dc:date.available

2016

Author dc:creator

• Grimes, Brian A.

• Chemical Engineering

Repository record dc:identifier

https://scholarsmine.mst.edu/doctoral_dissertations/1596

OAI identifier oai:identifier

oai:scholarsmine.mst.edu:doctoral_dissertations-2598