{"id":{"repo_id":"msu","oai_identifier":"oai:d.lib.msu.edu:dnp_70"},"canonical_url":"https://search.dev.ndltd.org/etd/msu/oai:d.lib.msu.edu:dnp_70","repository":{"repo_id":"msu","name":"Michigan State University","base_url":"https://d.lib.msu.edu/oai"},"display":{"title":"Improving best practice guidelines for Xylazine-related wounds : a DNP project","abstract":"Problem: Xylazine, an alpha 2-agonist used in veterinary medicine, is increasingly found in illicit drugs, leading to severe cutaneous injuries among substance use disorder (SUD) patients. These wounds are often misidentified and improperly treated due to a lack of awareness and guidelines among healthcare providers. Purpose: This project aims to develop and implement best practice guidelines for the identification, prevention, and treatment of xylazine-related wounds in SUD patients, particularly those accessing care through mobile health clinics (MHCs). Methods: A comprehensive literature review was conducted to identify existing evidence on xylazine-related wounds. A screening tool and wound care guidelines were developed and implemented in a nonprofit mobile clinic (NPMC) in southeastern Michigan. Patients identified as \"at-risk\" were provided with one-on-one education sessions, and healthcare providers received training on the new guidelines. Results: Implementing the screening tool and wound care guidelines improved the identification and management of xylazine-related wounds. Patients reported increased awareness of the risks associated with xylazine use and a higher likelihood of seeking early care for new wounds. Healthcare providers reported increased confidence in identifying and treating these wounds. Conclusions: The project successfully improved the identification and management of xylazine-related wounds in SUD patients. The findings highlight the importance of targeted education and training for patients and healthcare providers to address the unique challenges posed by xylazine use.","abstract_html":"Problem: Xylazine, an alpha 2-agonist used in veterinary medicine, is increasingly found in illicit drugs, leading to severe cutaneous injuries among substance use disorder (SUD) patients. These wounds are often misidentified and improperly treated due to a lack of awareness and guidelines among healthcare providers. Purpose: This project aims to develop and implement best practice guidelines for the identification, prevention, and treatment of xylazine-related wounds in SUD patients, particularly those accessing care through mobile health clinics (MHCs). Methods: A comprehensive literature review was conducted to identify existing evidence on xylazine-related wounds. A screening tool and wound care guidelines were developed and implemented in a nonprofit mobile clinic (NPMC) in southeastern Michigan. Patients identified as "at-risk" were provided with one-on-one education sessions, and healthcare providers received training on the new guidelines. Results: Implementing the screening tool and wound care guidelines improved the identification and management of xylazine-related wounds. Patients reported increased awareness of the risks associated with xylazine use and a higher likelihood of seeking early care for new wounds. Healthcare providers reported increased confidence in identifying and treating these wounds. Conclusions: The project successfully improved the identification and management of xylazine-related wounds in SUD patients. The findings highlight the importance of targeted education and training for patients and healthcare providers to address the unique challenges posed by xylazine use.","abstract_has_math":false,"creators":["Sauve, Stephanie"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":["Iseler, Jackie"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025","date_published":"2025","updated_at":"2026-07-24T03:16:39Z","subjects":["Substance abuse--Patients","Wounds and injuries--Diagnosis","Wounds and injuries--Treatment","Medical protocols","Xylazine"],"languages":["English"],"rights":["In Copyright"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["dnp:70","oclc:1569639929","local:R_3GlkKYjxEk4gy8R"],"render_values":[{"text":"dnp:70","href":null,"code":true},{"text":"oclc:1569639929","href":null,"code":true},{"text":"local:R_3GlkKYjxEk4gy8R","href":null,"code":true}]}]},"links":{"outbound_url":"https://doi.org/doi:10.25335/crd1-5n26","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Iseler, Jackie"]},{"key":"dc:creator","label":"Author","values":["Sauve, Stephanie"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:coverage","label":"Dc Coverage","values":["Michigan"]},{"key":"dc:date","label":"Dc Date","values":["2025"]},{"key":"dc:relation","label":"Dc Relation","values":["Doctor of Nursing Practice Projects"]},{"key":"dc:type","label":"Dc Type","values":["Text","Theses","Posters"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Substance abuse--Patients","Wounds and injuries--Diagnosis","Wounds and injuries--Treatment","Medical protocols","Xylazine"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["English"]},{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["dnp:70","oclc:1569639929","local:R_3GlkKYjxEk4gy8R","https://doi.org/doi:10.25335/crd1-5n26"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Problem: Xylazine, an alpha 2-agonist used in veterinary medicine, is increasingly found in illicit drugs, leading to severe cutaneous injuries among substance use disorder (SUD) patients. These wounds are often misidentified and improperly treated due to a lack of awareness and guidelines among healthcare providers. Purpose: This project aims to develop and implement best practice guidelines for the identification, prevention, and treatment of xylazine-related wounds in SUD patients, particularly those accessing care through mobile health clinics (MHCs). Methods: A comprehensive literature review was conducted to identify existing evidence on xylazine-related wounds. A screening tool and wound care guidelines were developed and implemented in a nonprofit mobile clinic (NPMC) in southeastern Michigan. Patients identified as \"at-risk\" were provided with one-on-one education sessions, and healthcare providers received training on the new guidelines. Results: Implementing the screening tool and wound care guidelines improved the identification and management of xylazine-related wounds. Patients reported increased awareness of the risks associated with xylazine use and a higher likelihood of seeking early care for new wounds. Healthcare providers reported increased confidence in identifying and treating these wounds. Conclusions: The project successfully improved the identification and management of xylazine-related wounds in SUD patients. The findings highlight the importance of targeted education and training for patients and healthcare providers to address the unique challenges posed by xylazine use.","Thesis (D.N.P.)--Michigan State University. Clinical nurse specialist, 2025","Includes bibliographical references"]},{"key":"dc:format","label":"Dc Format","values":["1 page","application/pdf"]},{"key":"dc:title","label":"Title","values":["Improving best practice guidelines for Xylazine-related wounds : a DNP project"]}]}],"canonical_facts":{"dc:contributor":["Iseler, Jackie"],"dc:coverage":["Michigan"],"dc:creator":["Sauve, Stephanie"],"dc:date":["2025"],"dc:description":["Problem: Xylazine, an alpha 2-agonist used in veterinary medicine, is increasingly found in illicit drugs, leading to severe cutaneous injuries among substance use disorder (SUD) patients. These wounds are often misidentified and improperly treated due to a lack of awareness and guidelines among healthcare providers. Purpose: This project aims to develop and implement best practice guidelines for the identification, prevention, and treatment of xylazine-related wounds in SUD patients, particularly those accessing care through mobile health clinics (MHCs). Methods: A comprehensive literature review was conducted to identify existing evidence on xylazine-related wounds. A screening tool and wound care guidelines were developed and implemented in a nonprofit mobile clinic (NPMC) in southeastern Michigan. Patients identified as \"at-risk\" were provided with one-on-one education sessions, and healthcare providers received training on the new guidelines. Results: Implementing the screening tool and wound care guidelines improved the identification and management of xylazine-related wounds. Patients reported increased awareness of the risks associated with xylazine use and a higher likelihood of seeking early care for new wounds. Healthcare providers reported increased confidence in identifying and treating these wounds. Conclusions: The project successfully improved the identification and management of xylazine-related wounds in SUD patients. The findings highlight the importance of targeted education and training for patients and healthcare providers to address the unique challenges posed by xylazine use.","Thesis (D.N.P.)--Michigan State University. Clinical nurse specialist, 2025","Includes bibliographical references"],"dc:format":["1 page","application/pdf"],"dc:identifier":["dnp:70","oclc:1569639929","local:R_3GlkKYjxEk4gy8R","https://doi.org/doi:10.25335/crd1-5n26"],"dc:language":["English"],"dc:relation":["Doctor of Nursing Practice Projects"],"dc:rights":["In Copyright"],"dc:subject":["Substance abuse--Patients","Wounds and injuries--Diagnosis","Wounds and injuries--Treatment","Medical protocols","Xylazine"],"dc:title":["Improving best practice guidelines for Xylazine-related wounds : a DNP project"],"dc:type":["Text","Theses","Posters"]},"updated_at":"2026-07-24T03:16:39Z"}