{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/78365"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/78365","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Bio-inspired collective analog computation","abstract":"In this thesis, I present electronic circuit systems that mimic collective analog com- putation found in biology. By combining the advantages of analog and digital computation, these systems can lead to highly complex, rapid, and energy-efficient systems such as an analog supercomputer that is capable of simulating a great number of bio- chemical reactions in cells. To this end, I first implement a neuron-inspired collective analog adder in a standard 0.5 [mu]m CMOS process. It serves as a prototype system that visualizes fundamental design ideas and techniques for building a collective analog computation system. Next, I build a cell-inspired analog circuit system which efficiently models bacterial genetic circuits in a cell, which can provide a powerful modeling and simulation tool for the design and analysis of circuits in synthetic and systems biology.","abstract_html":"In this thesis, I present electronic circuit systems that mimic collective analog com- putation found in biology. By combining the advantages of analog and digital computation, these systems can lead to highly complex, rapid, and energy-efficient systems such as an analog supercomputer that is capable of simulating a great number of bio- chemical reactions in cells. To this end, I first implement a neuron-inspired collective analog adder in a standard 0.5 [mu]m CMOS process. It serves as a prototype system that visualizes fundamental design ideas and techniques for building a collective analog computation system. Next, I build a cell-inspired analog circuit system which efficiently models bacterial genetic circuits in a cell, which can provide a powerful modeling and simulation tool for the design and analysis of circuits in synthetic and systems biology.","abstract_has_math":false,"creators":["Woo, Sung Sik, Ph. D. Massachusetts Institute of Technology"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science.","school":null,"contributors":[],"advisors":["Rahul Sarpeshkar."],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-22T22:21:02Z","subjects":["Electrical Engineering and Computer Science."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/78365","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Rahul Sarpeshkar."]},{"key":"dc:contributor.department","label":"Department","values":["Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science."]},{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science."]},{"key":"dc:creator","label":"Author","values":["Woo, Sung Sik, Ph. D. 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The certified thesis is available in the Institute Archives and Special Collections.","Cataloged from student-submitted PDF version of thesis.","Includes bibliographical references (p. 101-102)."]},{"key":"dc:description.abstract","label":"Abstract","values":["In this thesis, I present electronic circuit systems that mimic collective analog com- putation found in biology. By combining the advantages of analog and digital computation, these systems can lead to highly complex, rapid, and energy-efficient systems such as an analog supercomputer that is capable of simulating a great number of bio- chemical reactions in cells. To this end, I first implement a neuron-inspired collective analog adder in a standard 0.5 [mu]m CMOS process. It serves as a prototype system that visualizes fundamental design ideas and techniques for building a collective analog computation system. Next, I build a cell-inspired analog circuit system which efficiently models bacterial genetic circuits in a cell, which can provide a powerful modeling and simulation tool for the design and analysis of circuits in synthetic and systems biology."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.M."]},{"key":"dc:title","label":"Title","values":["Bio-inspired collective analog computation"]}]}],"canonical_facts":{"dc:contributor.advisor":["Rahul Sarpeshkar."],"dc:contributor.department":["Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science."],"dc:contributor.other":["Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science."],"dc:creator":["Woo, Sung Sik, Ph. D. 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To this end, I first implement a neuron-inspired collective analog adder in a standard 0.5 [mu]m CMOS process. It serves as a prototype system that visualizes fundamental design ideas and techniques for building a collective analog computation system. Next, I build a cell-inspired analog circuit system which efficiently models bacterial genetic circuits in a cell, which can provide a powerful modeling and simulation tool for the design and analysis of circuits in synthetic and systems biology."],"dc:description.degree":["S.M."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/78365"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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