Frequency domain model-based intracranial pressure estimation

Elevation of intracranial pressure (ICP), the pressure of the fluid surrounding the brain, can require urgent medical attention. Current methods for determining ICP are invasive, require neurosurgical expertise, and can lead to infection. ICP measurement is therefore limited to the sickest patients, though many others could potentially benefit from availability of this vital sign. We present a frequency-domain approach to ICP estimation using a simple lumped, linear time-invariant model of cerebrovascular dynamics. Preliminary results from 28 records of patients with severe traumatic brain injury are presented and discussed. Suggestions for future work to improve the estimation algorithm are proposed.

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2012

Author dc:creator

• Hwang, Irena T. (Irena Tammy)

Advisor dc:contributor.advisor

• George C. Verghese and Faisal M. Kashif.

• Electrical Engineering and Computer Science.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/77016

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/77016