{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/73439"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/73439","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"High reliability performance in Amgen Engineering","abstract":"Amgen is in the midst of a transformative initiative to become operationally more efficient. For Amgen Engineering, this initiative has prompted a reevaluation of the entire organization and brought to light the need to standardize, define processes, and promote a culture wherein reliable outcomes are both possible and expected. One way to accomplish this is by evaluating and then implementing the concepts of High Reliability Organization (HRO). This thesis focuses on using concepts such as HRO to evaluate the Engineering organization at Amgen and then provide tools, frameworks, and recommendations for driving increased reliability and greater process maturity across Amgen's entire asset lifecycle (Plan, Build/Lease, Operate/Maintain, Reinvest/Dispose). Three main deliverables resulted from this project's reliability efforts. The first deliverable is a set of recommendations and strategies to help the Engineering organization operate as an HRO. The second deliverable is an enhanced process maturity model that implements reliability concepts to drive the maturity of Engineering's business processes. The model better defines criteria for each level of maturity and will be used as a guidance tool for organizational advancement in the coming years. The last deliverable focuses on the maintain portion of the asset lifecycle, and is a Maintenance Excellence Roadmap that defines what maintenance excellence looks like and provides a strategy to best utilize the systems and tools that Amgen has in place, and will need in the future, to get there.","abstract_html":"Amgen is in the midst of a transformative initiative to become operationally more efficient. For Amgen Engineering, this initiative has prompted a reevaluation of the entire organization and brought to light the need to standardize, define processes, and promote a culture wherein reliable outcomes are both possible and expected. One way to accomplish this is by evaluating and then implementing the concepts of High Reliability Organization (HRO). This thesis focuses on using concepts such as HRO to evaluate the Engineering organization at Amgen and then provide tools, frameworks, and recommendations for driving increased reliability and greater process maturity across Amgen's entire asset lifecycle (Plan, Build/Lease, Operate/Maintain, Reinvest/Dispose). Three main deliverables resulted from this project's reliability efforts. The first deliverable is a set of recommendations and strategies to help the Engineering organization operate as an HRO. The second deliverable is an enhanced process maturity model that implements reliability concepts to drive the maturity of Engineering's business processes. The model better defines criteria for each level of maturity and will be used as a guidance tool for organizational advancement in the coming years. The last deliverable focuses on the maintain portion of the asset lifecycle, and is a Maintenance Excellence Roadmap that defines what maintenance excellence looks like and provides a strategy to best utilize the systems and tools that Amgen has in place, and will need in the future, to get there.","abstract_has_math":false,"creators":["Bolgren, Daniel (Daniel Reade)"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Leaders for Global Operations Program at MIT","school":null,"contributors":[],"advisors":["Robert T. Haslam and Steven Spear."],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012","date_published":"2012","updated_at":"2026-07-22T22:21:04Z","subjects":["Sloan School of Management.","Chemical Engineering.","Leaders for Global Operations Program."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. 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For Amgen Engineering, this initiative has prompted a reevaluation of the entire organization and brought to light the need to standardize, define processes, and promote a culture wherein reliable outcomes are both possible and expected. One way to accomplish this is by evaluating and then implementing the concepts of High Reliability Organization (HRO). This thesis focuses on using concepts such as HRO to evaluate the Engineering organization at Amgen and then provide tools, frameworks, and recommendations for driving increased reliability and greater process maturity across Amgen's entire asset lifecycle (Plan, Build/Lease, Operate/Maintain, Reinvest/Dispose). Three main deliverables resulted from this project's reliability efforts. The first deliverable is a set of recommendations and strategies to help the Engineering organization operate as an HRO. The second deliverable is an enhanced process maturity model that implements reliability concepts to drive the maturity of Engineering's business processes. The model better defines criteria for each level of maturity and will be used as a guidance tool for organizational advancement in the coming years. The last deliverable focuses on the maintain portion of the asset lifecycle, and is a Maintenance Excellence Roadmap that defines what maintenance excellence looks like and provides a strategy to best utilize the systems and tools that Amgen has in place, and will need in the future, to get there."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.M.","M.B.A."]},{"key":"dc:title","label":"Title","values":["High reliability performance in Amgen Engineering"]}]}],"canonical_facts":{"dc:contributor.advisor":["Robert T. Haslam and Steven Spear."],"dc:contributor.department":["Leaders for Global Operations Program at MIT","Massachusetts Institute of Technology. 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