Using value stream mapping to improve documentation processes in the biopharmacutical industry

This thesis describes how a 55% reduction in error rate and a 92% decrease in cycle-time were achieved in a batch production records process in a biotech manufacturing facility by utilization of value-stream mapping. The project focuses on careful analysis of the current state of a batch production record review process, including an in-depth value stream map, to identify sources of rework and waste in the current process. Analysis of the value stream map led to the recommendation of real-time review of the documentation by Quality Assurance and Manufacturing on the production floor, enabling significant cycle-time and error rate improvements.

Department dc:contributor.department

Leaders for Global Operations Program at MIT

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2010

Author dc:creator

• Ford, Rebecca (Rebecca Lynn)

Advisor dc:contributor.advisor

• Charles L. Cooney and Don Rosenfield.

• Sloan School of Management.
• Chemical Engineering.
• Leaders for Global Operations Program.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/59184

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/59184