Studies on the synthesis of cyclohexynes for inter- and intramolecular cycloaddition reactions

Strained cycloalkynes have been of interest to organic chemists for many years due to their exotic structure and their potential utility as synthetic building blocks. This thesis examines the generation of cyclohexyne derivatives and their reactivity in inter- and intramolecular cycloadditions. Several strategies were investigated to generate substrates for the intramolecular trapping of the cyclohexynes. In addition, simple cyclohexyne derivatives were prepared and two cases of intermolecular trapping are reported.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Chemistry.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2010

Author dc:creator

• Crosswhite, Cynthia K. (Cynthaia Kathleen)

Advisor dc:contributor.advisor

• Rick L. Danheiser.

• Chemistry.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/57982

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/57982