{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/45810"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/45810","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Collagen and hyaluronic acid interpenetrating polymer networks for tissue engineering","abstract":"Interpenetrating Polymer Networks (IPNs) represent a strategy for combining the properties of several polymeric materials into a single network. In this thesis, collagen and methacrylated hyaluronic acid are combined in IPNs to produce a range of new biocompatible. The fabrication method allows for control of compressive strength of the IPN hydrogels. The materials are confirmed to be homogeneous at microscopic scales with fluorescent techniques. The IPNs are used for cell encapsulation and have the potential to be used for surface cell culture. The mechanical properties can be adjusted to match those of cardiac tissue. Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications.","abstract_html":"Interpenetrating Polymer Networks (IPNs) represent a strategy for combining the properties of several polymeric materials into a single network. In this thesis, collagen and methacrylated hyaluronic acid are combined in IPNs to produce a range of new biocompatible. The fabrication method allows for control of compressive strength of the IPN hydrogels. The materials are confirmed to be homogeneous at microscopic scales with fluorescent techniques. The IPNs are used for cell encapsulation and have the potential to be used for surface cell culture. The mechanical properties can be adjusted to match those of cardiac tissue. Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications.","abstract_has_math":false,"creators":["Brigham, Mark D"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.","school":null,"contributors":[],"advisors":["Ali Khademhosseini and Utkan Demirci."],"committee_chairs":[],"committee_members":[],"year":2007,"date_issued":"2007","date_published":"2007","updated_at":"2026-07-22T22:22:22Z","subjects":["Electrical Engineering and Computer Science."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["M.Eng."]},{"key":"dc:title","label":"Title","values":["Collagen and hyaluronic acid interpenetrating polymer networks for tissue engineering"]}]}],"canonical_facts":{"dc:contributor.advisor":["Ali Khademhosseini and Utkan Demirci."],"dc:contributor.department":["Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science."],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science."],"dc:creator":["Brigham, Mark D"],"dc:date.accessioned":["2009-06-30T16:20:54Z"],"dc:date.available":["2009-06-30T16:20:54Z"],"dc:date.issued":["2007"],"dc:description":["Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2007.","Includes bibliographical references (leaves 68-70)."],"dc:description.abstract":["Interpenetrating Polymer Networks (IPNs) represent a strategy for combining the properties of several polymeric materials into a single network. In this thesis, collagen and methacrylated hyaluronic acid are combined in IPNs to produce a range of new biocompatible. The fabrication method allows for control of compressive strength of the IPN hydrogels. The materials are confirmed to be homogeneous at microscopic scales with fluorescent techniques. The IPNs are used for cell encapsulation and have the potential to be used for surface cell culture. The mechanical properties can be adjusted to match those of cardiac tissue. Thus, when combined with the properties of biocompatibility, viable cell encapsulation, and cell culture, the collagenMeHA IPN hydrogels represent a powerful new material for tissue engineering applications."],"dc:description.degree":["M.Eng."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/45810"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Electrical Engineering and Computer Science."],"dc:title":["Collagen and hyaluronic acid interpenetrating polymer networks for tissue engineering"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:22:22Z"}