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Massachusetts Institute of Technology

Developing the Broad Process Excellence Program

Abstract

dc:description.abstract

This thesis is based on the author's experience as an intern at the Broad Institute of MIT and Harvard. The Broad Institute has been working on applying and implementing traditional manufacturing process improvement tools to customize and select tools that can be adapted to its needs. Its unique production environment necessitates the requirement to customize and select tools that can be adapted to its needs. The objective of the thesis is to identify such tools and recommend methods to sustain them. The scope includes the following: * Conduct a benchmarking survey to understand what other organizations are doing in the area. * Conduct a stakeholder analysis involving relevant team members in Sequencing Operations. * Design a system that brings together the lessons learned from the benchmarking and stakeholder analysis exercises. * Conduct a project to showcase some of the tools. The objective of the project is to identify key process levers and improve the performance of the Duncan Cycler, a key DNA processing step. This problem solving exercise acts as a proxy for situations where tools recommended by the program can be used.

Degree

thesis:*
Department dc:contributor.department
Leaders for Manufacturing Program at MIT
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2007

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Datta, Subhrangshu, 1975-
Advisor dc:contributor.advisor
  • Roy E. Welsch and Deborah Nightingale.

Subjects

dc:subject × 3

Rights

dc:rights
Statement dc:rights
  • M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/1721.1/39865
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/39865

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Datta, Subhrangshu, 1975-. Developing the Broad Process Excellence Program. Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/39865