Microbubble cell actuator

The field of microsystems technology is rapidly growing, and expanding its horizons to applications in bioengineering. Currently, there are no cell analysis systems that facilitate the collection of dynamic responses for a large number of cells, and sorting based on those results. A cell chip has been fabricated in pursuit of this goal, which can capture particles in an array, hold them against a flow, and selectively release them. The release mechanism uses a vapor microbubble as a means of volume expansion to create a jet of fluid that ejects a particle. The theory, design, and testing are described, and successful operation of the device is demonstrated. Applications and suggestions for future work are discussed.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Mechanical Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

1999

Author dc:creator

• Braff, Rebecca A. (Rebecca Alice)

Advisor dc:contributor.advisor

• Mehmet Toner and Martha Gray.

• Mechanical Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/38276

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/38276