{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/36723"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/36723","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Creation of a database for evaluating the effect of genetic intellectual property on genetic diagnostic testing","abstract":"In this study, we explore the impact of gene-based patents on the pricing and availability of genetic diagnostic tests. We also explore the nature and scope of the genetic diagnostics industry itself. Through data mining of the GeneTests database and gathering of pricing and procedure information from over 51 laboratories (using a range of sources including phone interviews), we created a unique database that links pricing, procedure and availability information for each sequencing-based gene diagnostic test offered in the US. In addition, we linked relevant gene-based patents to each gene in our database. Our results indicate a correlation between gene patents and test pricing, with an average non-patented test price of -$1330.31 (121 entries) compared to an average price of -$1419.58 for tests associated with gene patents (137 entries).","abstract_html":"In this study, we explore the impact of gene-based patents on the pricing and availability of genetic diagnostic tests. We also explore the nature and scope of the genetic diagnostics industry itself. Through data mining of the GeneTests database and gathering of pricing and procedure information from over 51 laboratories (using a range of sources including phone interviews), we created a unique database that links pricing, procedure and availability information for each sequencing-based gene diagnostic test offered in the US. In addition, we linked relevant gene-based patents to each gene in our database. Our results indicate a correlation between gene patents and test pricing, with an average non-patented test price of -$1330.31 (121 entries) compared to an average price of -$1419.58 for tests associated with gene patents (137 entries).","abstract_has_math":true,"creators":["Murray, Philip (Philip E.)"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Mechanical Engineering.","school":null,"contributors":[],"advisors":["Fiona Murray."],"committee_chairs":[],"committee_members":[],"year":2006,"date_issued":"2006","date_published":"2006","updated_at":"2026-07-22T22:22:19Z","subjects":["Mechanical Engineering."],"languages":["eng"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/36723","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Fiona Murray."]},{"key":"dc:contributor.department","label":"Department","values":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."]},{"key":"dc:contributor.other","label":"Dc Contributor Other","values":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."]},{"key":"dc:creator","label":"Author","values":["Murray, Philip (Philip E.)"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2007-03-12T17:47:48Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2007-03-12T17:47:48Z"]},{"key":"dc:date.issued","label":"Date","values":["2006"]},{"key":"dc:publisher","label":"Institution","values":["Massachusetts Institute of Technology"]},{"key":"dc:type","label":"Dc Type","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Mechanical Engineering."]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://dspace.mit.edu/handle/1721.1/7582"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/1721.1/36723"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.","Includes bibliographical references (leaves 33-34)."]},{"key":"dc:description.abstract","label":"Abstract","values":["In this study, we explore the impact of gene-based patents on the pricing and availability of genetic diagnostic tests. We also explore the nature and scope of the genetic diagnostics industry itself. Through data mining of the GeneTests database and gathering of pricing and procedure information from over 51 laboratories (using a range of sources including phone interviews), we created a unique database that links pricing, procedure and availability information for each sequencing-based gene diagnostic test offered in the US. In addition, we linked relevant gene-based patents to each gene in our database. Our results indicate a correlation between gene patents and test pricing, with an average non-patented test price of -$1330.31 (121 entries) compared to an average price of -$1419.58 for tests associated with gene patents (137 entries)."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.B."]},{"key":"dc:title","label":"Title","values":["Creation of a database for evaluating the effect of genetic intellectual property on genetic diagnostic testing"]}]}],"canonical_facts":{"dc:contributor.advisor":["Fiona Murray."],"dc:contributor.department":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:contributor.other":["Massachusetts Institute of Technology. Dept. of Mechanical Engineering."],"dc:creator":["Murray, Philip (Philip E.)"],"dc:date.accessioned":["2007-03-12T17:47:48Z"],"dc:date.available":["2007-03-12T17:47:48Z"],"dc:date.issued":["2006"],"dc:description":["Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.","Includes bibliographical references (leaves 33-34)."],"dc:description.abstract":["In this study, we explore the impact of gene-based patents on the pricing and availability of genetic diagnostic tests. We also explore the nature and scope of the genetic diagnostics industry itself. Through data mining of the GeneTests database and gathering of pricing and procedure information from over 51 laboratories (using a range of sources including phone interviews), we created a unique database that links pricing, procedure and availability information for each sequencing-based gene diagnostic test offered in the US. In addition, we linked relevant gene-based patents to each gene in our database. Our results indicate a correlation between gene patents and test pricing, with an average non-patented test price of -$1330.31 (121 entries) compared to an average price of -$1419.58 for tests associated with gene patents (137 entries)."],"dc:description.degree":["S.B."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/36723"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Mechanical Engineering."],"dc:title":["Creation of a database for evaluating the effect of genetic intellectual property on genetic diagnostic testing"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:22:19Z"}