Market application of a novel stent-based patency monitor to the management of ischemic vascular disease

The use of stents following angioplasty in ischemic arterial beds is limited by complications and continuing vascular deterioration. A phenomenon called stent restenosis post procedure exists which puts patients at a relatively high risk for vessel stenosis and occlusion. Stent restenosis may eventually lead to clinical symptoms such as myocardial infarction, stroke or limb loss, and if overlooked might lead to death. Within five years of stenting, a significant portion of patients require additional surgical intervention. A novel stent-based, implantable, and wireless approach for real-time monitoring of vessel patency at the site of coronary stents is proposed, will provide a measure of efficacy of stenting and of the pharmacologic regiment to mitigate the risk of vessel stenosis and narrowing due to the underlying. The purpose of this thesis is to explore and test the Hypotheses that there is a market for a direct, non-invasive monitoring of vessel patency at the site of a coronary stent; and that an implantable, wireless, stent-based device to monitor blood flow rate through a coronary stent can be designed and built.

Department dc:contributor.department

Harvard University--MIT Division of Health Sciences and Technology.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2006

Author dc:creator

• Schori, Baruch

Advisor dc:contributor.advisor

• Richard J. Cohen and T. Forchet Dagi.

• Harvard University--MIT Division of Health Sciences and Technology.
• Sloan School of Management.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/35516

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/35516