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Massachusetts Institute of Technology

Image guidance in cardiac electrophysiology

Abstract

dc:description.abstract

Cardiac arrhythmias are characterized by a disruption or abnormal conduction of electrical signals within the heart. Treatment of arrhythmias has dramatically evolved over the past half-century, and today, minimally-invasive catheter-based therapy is the preferred method of eliminating arrhythmias. Using an electroanatomical (EA) mapping system, which precisely tracks the position of catheters inside the patient's body, it is possible to construct three-dimensional maps of the ventricular and atrial chambers of the heart. Each point of these maps is annotated based on bioelectrical signals recorded from the electrodes located at the tip of the catheter. These maps are then used to guide catheter ablation within the heart. However, the electroanatomical mapping procedure results in relatively sparse sampling of the heart and a significant amount of time and skill are require to generate these maps. In this thesis, we present our software system for the integration of pre-operative, patient-specific magnetic resonance (MR) or computed tomography (CT) imaging data with real-time electroanatomical mapping (EAM) information.

Degree

thesis:*
Department dc:contributor.department
Harvard University--MIT Division of Health Sciences and Technology.
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2006

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Malchano, Zachary John
Advisor dc:contributor.advisor
  • Vivek Y. Reddy, William M. Wells, III and W. Eric L. Grimson.

Subjects

dc:subject × 1

Rights

dc:rights
Statement dc:rights
  • M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/1721.1/35515
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/35515

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Malchano, Zachary John. Image guidance in cardiac electrophysiology. Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/35515