BioDig : architecture for integrating heterogeneous biological data repositories using ontologies

High-throughput experiments generate vast quantities of biological information that are stored in autonomous data repositories distributed across the World Wide Web. There exists a need to integrate information from multiple data repositories for the purposes of data mining; however, current methods of integration require a significant amount of manual work that is often tedious and time consuming. The thesis proposes a flexible architecture that facilitates the automation of data integration from multiple heterogeneous biological data repositories using ontologies. The design uses ontologies to resolve the semantic conflicts that usually hinder schema integration and searching for information. The architecture implemented successfully demonstrates how ontologies facilitate the automation of data integration from multiple data repositories. Nevertheless, many optimizations to increase the performance of the system were realized during the implementation of various components in the architecture and are described in the thesis.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2005

Author dc:creator

• Chou, Howard H

Advisor dc:contributor.advisor

• C. Forbes Dewey, Jr.

• Electrical Engineering and Computer Science.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/33116

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/33116