Compatibility and toxicity of polymer-coated magnetic nanoparticles on mammalian cell systems

(cont.) produced normal growth curves in the presence of particles. However, the particles do still exhibit some toxicity towards the cells, as the maximum cell density of cells cultured with particles does not reach that of control cultures. Both particles were found to increase the oxygen transfer in an aqueous solution. A 1.5% solution of particle A enhanced the oxygen transfer 41.8% over the control, water, while 1.4% particle B enhanced 15.9% over the control. While particle A has a better effect on oxygen transfer, this particle is not suitable to be used with mammalian cell cultures as it is highly toxic.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Chemical Engineering.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2005

Author dc:creator

• Kral, Kelly M., 1979-

Advisor dc:contributor.advisor

• Daniel I.C. Wang.

• Chemical Engineering.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/28850

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/28850