{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/28688"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/28688","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Efficiency of background suppression for arterial spin labeling","abstract":"Arterial spin labeling (ASL), a technique developed for the measurement of local tissue perfusion with MRI, is heavily dependent on distinguishing irrelevant static tissue signal from the labeled blood. Background suppression can greatly reduce motion and other sources of noise in Arterial Spin Labeling MRI. More sophisticated background suppression strategies with many inversion pulses may decrease the ASL signal causing reduced signal-to-noise ratios and quantitative accuracy. Numerical simulations and in-vivo measurements were used to measure the inefficiency of different adiabatic inversion pulses and to optimize pulse selection. The results emphasize the high potential efficiency of adiabatic inversion pulses but also the limited optimal range of pulse parameters.","abstract_html":"Arterial spin labeling (ASL), a technique developed for the measurement of local tissue perfusion with MRI, is heavily dependent on distinguishing irrelevant static tissue signal from the labeled blood. Background suppression can greatly reduce motion and other sources of noise in Arterial Spin Labeling MRI. More sophisticated background suppression strategies with many inversion pulses may decrease the ASL signal causing reduced signal-to-noise ratios and quantitative accuracy. Numerical simulations and in-vivo measurements were used to measure the inefficiency of different adiabatic inversion pulses and to optimize pulse selection. The results emphasize the high potential efficiency of adiabatic inversion pulses but also the limited optimal range of pulse parameters.","abstract_has_math":false,"creators":["Garcia, Dairon, 1980-"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.","school":null,"contributors":[],"advisors":["David Alsop."],"committee_chairs":[],"committee_members":[],"year":2005,"date_issued":"2005","date_published":"2005","updated_at":"2026-07-22T22:21:08Z","subjects":["Electrical Engineering and Computer Science."],"languages":["en_US"],"rights":["M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 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