An engineering model of lower thalamo-cortico-basal ganglionic circuit function

An engineering model of lower thalamo-cortico-basal ganglionic circuit functionality was extended and tested. This model attempts to explain the circuitry of the basal ganglia, examine its functional properties, and integrate these properties into an understanding of the diseases of the basal ganglia, such as Parkinson's disease and Huntington's disease. Using this model, simulations of various movements were developed, specifically those of the following: 1) one-step, cruise movements, 2) asynchronous, cruise movements, and 3) sequential cruise movements. Results of these movements include simulated movements of both normal patients and patients with movement disorders.

Department dc:contributor.department

Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2003

Author dc:creator

• Lim, Eugene J. (Eugene Jungsud), 1980-

Advisor dc:contributor.advisor

• Steven G. Massaquoi.

• Electrical Engineering and Computer Science.

Statement dc:rights

• M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

en_US

Handle dc:identifier.uri

http://hdl.handle.net/1721.1/28458

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/28458