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Massachusetts Institute of Technology

Resilient by Design: A Supply Chain Digitalization Journey

Abstract

dc:description.abstract

In an era where supply chain disruptions have become increasingly relevant due to geopolitical and environmental factors, resilience has emerged as a critical focus for organizations worldwide. This is particularly true in the pharmaceutical sector, where ensuring an uninterrupted supply of medical products is not only a business necessity but also a moral imperative, given the direct impact on patients’ health and well-being. This thesis presents the development of a digital tool designed to enhance the resilience of AstraZeneca’s supply chain, employing a design thinking approach. The tool leverages simulation and business intelligence, providing a versatile platform for conducting stress tests and evaluating response mechanisms across a spectrum of scenarios. This capability is instrumental in refining business continuity plans and informing strategic decisions on disruption response and capacity investments. While the tool was initially conceived to address the specific needs of AstraZeneca, its architecture is inherently generic and modular. This deliberate design choice ensures that the tool can be seamlessly adapted and scaled for use across various industries, transcending the initial scope of application. Additionally, the tool lays a solid foundation for future developments in the realm of supply chain digital twins. The thesis also contributes a comprehensive framework for boosting supply chain resilience through the lens of digitalization. It offers a strategic blueprint that organizations can adopt to proactively navigate and mitigate the intricacies of global supply chain disruptions.

Degree

thesis:*
Name thesis:degree_name
Master
Department dc:contributor.department
Sloan School of Management
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2024

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Vela González, Carlos David
Advisors dc:contributor.advisor
  • Roemer, Thomas
  • Simchi-Levi, David

Rights

dc:rights
Statement dc:rights
  • In Copyright - Educational Use Permitted
  • Copyright retained by author(s)

Identifiers

dc:identifier.*
Handle dc:identifier.uri
https://hdl.handle.net/1721.1/156009
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/156009

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
related terms
citation

Vela González, Carlos David. Resilient by Design: A Supply Chain Digitalization Journey. Massachusetts Institute of Technology, 2024. https://hdl.handle.net/1721.1/156009