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Massachusetts Institute of Technology

Pre-trained Language Models for Clinical Systematic Literature Reviews

Abstract

dc:description.abstract

Although systematic literature reviews play a critical role in clinical-based decision making, manual methods for information extraction can sometimes take prohibitively long. In this work, we first describe the construction of datasets in two distinct clinical domains containing randomized trials and observational studies. We then utilize these two datasets to benchmark the performance of Pretrained Language Model (PLM) based entity and relation extraction models as well as the effect of domain specific pre-training prior to their fine-tuning. Our results show evidence to the effectiveness of pre-training using masked language modeling (MLM), a sentence-level proxy task, on boosting the performance of fine-tuned models on both inter- and intra-sentence level information extraction tasks.

Degree

thesis:*
Name thesis:degree_name
Master
Department dc:contributor.department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2022

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Ortiz, Juan M. Ochoa
Advisor dc:contributor.advisor
  • Barzilay, Regina

Rights

dc:rights
Statement dc:rights
  • In Copyright - Educational Use Permitted
  • Copyright MIT

Identifiers

dc:identifier.*
Handle dc:identifier.uri
https://hdl.handle.net/1721.1/143177
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/143177

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
related terms
citation

Ortiz, Juan M. Ochoa. Pre-trained Language Models for Clinical Systematic Literature Reviews. Massachusetts Institute of Technology, 2022. https://hdl.handle.net/1721.1/143177