Rapid time-resolved brain imaging with multiple clinical contrasts using wave-shuffling

Magnetic Resonance Imaging (MRI) is a non-invasive but slow biomedical imaging modality that produces images of multiple desirable contrasts. Currently, multiple receive channels are used in MRI to exploit redundancy and sample fewer data points for faster acquisition. Wave-CAIPI is a recently introduced technique that modifies the acquisition scheme in a manner that improves the effectiveness of the receive channels, allowing for higher rates of acceleration. In this work, the principle behind Wave-CAIPI is applied to a compressed-sensing technique called Shuffling. In Shuffling, the spatial and temporal axis are randomly sampled and the data is reconstructed with temporal subspace constraints, yielding a time-series of images with desirable contrast. Combining Wave-CAIPI and Shuffling achieves rapid, time-resolved imaging of brain at 1mm-isotropic spatial resolution in clinically feasible times.

Name thesis:degree_name

Master

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2019

Author dc:creator

• Iyer, Siddharth(Siddharth Srinivasan)

Advisor dc:contributor.advisor

• Kawin Setsompop.

• Electrical Engineering and Computer Science.

Statement dc:rights

• MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/1721.1/122700

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/122700