Design, development, and testing of a stochastically modulated Raman spectrometer

Detection of cancerous tumors and identification of counterfeit medications are just two examples that demonstrate the chemical specificity provided by Raman Spectroscopy. Yet, the widespread use of Raman Spectroscopy as an analytical tool has been limited to large bench-top systems in controlled laboratory environments. Existing technology, specifically in portable or handheld formats, suffers from a high false detection rate and relatively low sensitivity compared to other spectroscopic techniques. The present work addresses these issues through the design and development of a new system architecture that stochastically modulates the laser excitation wavelength. Small changes in excitation will proportionally shift the Raman scatter while having little effect on other spectral artifacts, including fluorescence.

Name thesis:degree_name

Doctoral

Department dc:contributor.department

Massachusetts Institute of Technology. Department of Mechanical Engineering

Grantor dc:publisher

Massachusetts Institute of Technology

Year dc:date.issued

2019

Author dc:creator

• Zervas, Michael Jay.

Advisor dc:contributor.advisor

• Ian W. Hunter.

• Mechanical Engineering.

Statement dc:rights

• MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.

Licence dc:rights.uri

• http://dspace.mit.edu/handle/1721.1/7582

Language dc:language.iso

eng

Handle dc:identifier.uri

https://hdl.handle.net/1721.1/122508

OAI identifier oai:identifier

oai:dspace.mit.edu:1721.1/122508