{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/119027"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/119027","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"Geometric and optical transformations of supramolecular host-guest amphiphiles","abstract":"Molecular self-assembly has been an area of recent interest due to its application in a variety of important contexts including drug delivery, regenerative medicine, energy applications, and others. Simultaneously, host-guest chemistry provides a robust and powerful mechanism for inducing switching on the molecular level. In this research, we demonstrate a new platform that combines molecular self-assembly of an amphiphilic chromophore guest molecule with its host molecule counterpart, CB[8] in water. We find that upon addition of CB[8] to a solution of the amphiphilic guest molecule, host-guest complexation occurs and a transition in the morphology of the observed self-assembled nanostructures occurs. Here we present the synthetic route to our amphiphilic guest molecule, in addition to the nanostructural characterization of the supramolecular nanostructures and the host-guest nanostructure by TEM, UV-Vis, and fluorescence spectra.","abstract_html":"Molecular self-assembly has been an area of recent interest due to its application in a variety of important contexts including drug delivery, regenerative medicine, energy applications, and others. Simultaneously, host-guest chemistry provides a robust and powerful mechanism for inducing switching on the molecular level. In this research, we demonstrate a new platform that combines molecular self-assembly of an amphiphilic chromophore guest molecule with its host molecule counterpart, CB[8] in water. We find that upon addition of CB[8] to a solution of the amphiphilic guest molecule, host-guest complexation occurs and a transition in the morphology of the observed self-assembled nanostructures occurs. Here we present the synthetic route to our amphiphilic guest molecule, in addition to the nanostructural characterization of the supramolecular nanostructures and the host-guest nanostructure by TEM, UV-Vis, and fluorescence spectra.","abstract_has_math":false,"creators":["Lo, Cynthia Tsien"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Department of Materials Science and Engineering.","school":null,"contributors":[],"advisors":["Julia Ortony."],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018","date_published":"2018","updated_at":"2026-07-22T22:20:53Z","subjects":["Materials Science and Engineering."],"languages":["eng"],"rights":["MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."],"rights_urls":["http://dspace.mit.edu/handle/1721.1/7582"],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/1721.1/119027","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Julia Ortony."]},{"key":"dc:contributor.department","label":"Department","values":["Massachusetts Institute of Technology. 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They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://dspace.mit.edu/handle/1721.1/7582"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/1721.1/119027"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2018.","This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.","Cataloged from student-submitted PDF version of thesis.","Includes bibliographical references (pages 30-31)."]},{"key":"dc:description.abstract","label":"Abstract","values":["Molecular self-assembly has been an area of recent interest due to its application in a variety of important contexts including drug delivery, regenerative medicine, energy applications, and others. Simultaneously, host-guest chemistry provides a robust and powerful mechanism for inducing switching on the molecular level. In this research, we demonstrate a new platform that combines molecular self-assembly of an amphiphilic chromophore guest molecule with its host molecule counterpart, CB[8] in water. We find that upon addition of CB[8] to a solution of the amphiphilic guest molecule, host-guest complexation occurs and a transition in the morphology of the observed self-assembled nanostructures occurs. Here we present the synthetic route to our amphiphilic guest molecule, in addition to the nanostructural characterization of the supramolecular nanostructures and the host-guest nanostructure by TEM, UV-Vis, and fluorescence spectra."]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.B."]},{"key":"dc:title","label":"Title","values":["Geometric and optical transformations of supramolecular host-guest amphiphiles"]}]}],"canonical_facts":{"dc:contributor.advisor":["Julia Ortony."],"dc:contributor.department":["Massachusetts Institute of Technology. Department of Materials Science and Engineering."],"dc:contributor.other":["Massachusetts Institute of Technology. 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In this research, we demonstrate a new platform that combines molecular self-assembly of an amphiphilic chromophore guest molecule with its host molecule counterpart, CB[8] in water. We find that upon addition of CB[8] to a solution of the amphiphilic guest molecule, host-guest complexation occurs and a transition in the morphology of the observed self-assembled nanostructures occurs. Here we present the synthetic route to our amphiphilic guest molecule, in addition to the nanostructural characterization of the supramolecular nanostructures and the host-guest nanostructure by TEM, UV-Vis, and fluorescence spectra."],"dc:description.degree":["S.B."],"dc:identifier.uri":["http://hdl.handle.net/1721.1/119027"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Materials Science and Engineering."],"dc:title":["Geometric and optical transformations of supramolecular host-guest amphiphiles"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:20:53Z"}