{"id":{"repo_id":"mit","oai_identifier":"oai:dspace.mit.edu:1721.1/114077"},"canonical_url":"https://search.dev.ndltd.org/etd/mit/oai:dspace.mit.edu:1721.1/114077","repository":{"repo_id":"mit","name":"MIT","base_url":"https://dspace.mit.edu/oai/request"},"display":{"title":"A prefrontal source of visual target enhancement in the macaque area V4","abstract":"The ventral pre-arcuate area (VPA) in the primate prefrontal cortex has recently been found to play an important role in feature-based selection of visual targets in the context of a naturalistic free-gaze visual search task. While VPA neuronal activation was found to be necessary for behavioral performance as well as target selection in the FEF, its role in the broader context of the visual system remains to be addressed. To this end, we have interrogated the role of the VPA in mediating the effects of feature attention in the macaque visual area V4 by recording in V4 with and without muscimol inactivation in the VPA. We report here that neuronal activation in the VPA is necessary for firing rate increases related to target selection in V4. KEYWORDS: feature attention, visual search, muscimol, neurophysiology","abstract_html":"The ventral pre-arcuate area (VPA) in the primate prefrontal cortex has recently been found to play an important role in feature-based selection of visual targets in the context of a naturalistic free-gaze visual search task. While VPA neuronal activation was found to be necessary for behavioral performance as well as target selection in the FEF, its role in the broader context of the visual system remains to be addressed. To this end, we have interrogated the role of the VPA in mediating the effects of feature attention in the macaque visual area V4 by recording in V4 with and without muscimol inactivation in the VPA. We report here that neuronal activation in the VPA is necessary for firing rate increases related to target selection in V4. KEYWORDS: feature attention, visual search, muscimol, neurophysiology","abstract_has_math":false,"creators":["Ghadooshahy, Azriel (Azriel Sion)"],"institution":"Massachusetts Institute of Technology","degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":"Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences.","school":null,"contributors":[],"advisors":["Robert Desimone."],"committee_chairs":[],"committee_members":[],"year":2017,"date_issued":"2017","date_published":"2017","updated_at":"2026-07-22T22:22:31Z","subjects":["Brain and Cognitive Sciences."],"languages":["eng"],"rights":["MIT theses are protected by copyright. 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They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."]},{"key":"dc:rights.uri","label":"Rights URI","values":["http://dspace.mit.edu/handle/1721.1/7582"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier.uri","label":"Identifier URI","values":["http://hdl.handle.net/1721.1/114077"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Thesis: S.M. in Neuroscience, Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, 2017.","Cataloged from PDF version of thesis.","Includes bibliographical references (page 16)."]},{"key":"dc:description.abstract","label":"Abstract","values":["The ventral pre-arcuate area (VPA) in the primate prefrontal cortex has recently been found to play an important role in feature-based selection of visual targets in the context of a naturalistic free-gaze visual search task. While VPA neuronal activation was found to be necessary for behavioral performance as well as target selection in the FEF, its role in the broader context of the visual system remains to be addressed. To this end, we have interrogated the role of the VPA in mediating the effects of feature attention in the macaque visual area V4 by recording in V4 with and without muscimol inactivation in the VPA. We report here that neuronal activation in the VPA is necessary for firing rate increases related to target selection in V4. KEYWORDS: feature attention, visual search, muscimol, neurophysiology"]},{"key":"dc:description.degree","label":"Dc Description Degree","values":["S.M. in Neuroscience"]},{"key":"dc:title","label":"Title","values":["A prefrontal source of visual target enhancement in the macaque area V4"]}]}],"canonical_facts":{"dc:contributor.advisor":["Robert Desimone."],"dc:contributor.department":["Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences."],"dc:contributor.other":["Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences."],"dc:creator":["Ghadooshahy, Azriel (Azriel Sion)"],"dc:date.accessioned":["2018-03-12T19:28:54Z"],"dc:date.available":["2018-03-12T19:28:54Z"],"dc:date.issued":["2017"],"dc:description":["Thesis: S.M. in Neuroscience, Massachusetts Institute of Technology, Department of Brain and Cognitive Sciences, 2017.","Cataloged from PDF version of thesis.","Includes bibliographical references (page 16)."],"dc:description.abstract":["The ventral pre-arcuate area (VPA) in the primate prefrontal cortex has recently been found to play an important role in feature-based selection of visual targets in the context of a naturalistic free-gaze visual search task. While VPA neuronal activation was found to be necessary for behavioral performance as well as target selection in the FEF, its role in the broader context of the visual system remains to be addressed. To this end, we have interrogated the role of the VPA in mediating the effects of feature attention in the macaque visual area V4 by recording in V4 with and without muscimol inactivation in the VPA. We report here that neuronal activation in the VPA is necessary for firing rate increases related to target selection in V4. KEYWORDS: feature attention, visual search, muscimol, neurophysiology"],"dc:description.degree":["S.M. in Neuroscience"],"dc:identifier.uri":["http://hdl.handle.net/1721.1/114077"],"dc:language.iso":["eng"],"dc:publisher":["Massachusetts Institute of Technology"],"dc:rights":["MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission."],"dc:rights.uri":["http://dspace.mit.edu/handle/1721.1/7582"],"dc:subject":["Brain and Cognitive Sciences."],"dc:title":["A prefrontal source of visual target enhancement in the macaque area V4"],"dc:type":["Thesis"]},"updated_at":"2026-07-22T22:22:31Z"}