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Massachusetts Institute of Technology

Product availability improvement for an analytical consumables supply chain : distribution and transportation

Abstract

dc:description.abstract

This thesis work focuses on supply chain operation optimization on column consumables at Waters Corporation in order to improve product availability to 95% to customers. This thesis project is conducted by collaboration of Han, Hua and Lee as a team through interviewing stakeholders, performing historical data analysis and model simulation. Hua's thesis focuses on safety stock allocation in different stages of column supply chain and Lee's thesis focuses on replenishment policy of products with consistent high demands and production policy for build-to-order products. This thesis focuses on improving product availability of products with relatively low demands and high variability. Due to the high uncertainty of geographical demand distribution and unbalanced on-hand inventory at major distribution centers around the world, pooling inventories into a single global distribution center is proposed to increase the company's capability to better fulfill customer requests. A single global distribution model is designed for Waters Corporation's column products to analyze the change in product availability. Further optimization on inventory using lot size-reorder point model with manufacturing lot size constraint reduces the total cost of inventory. As a result of constructing a single global distribution center, the product availability can be improved to 100% for products with current product availability of 70% or higher. For products with current product availability lower than 70%, an improvement to 80% to 90% can be achieved. The total on-hand inventory of all products within the scope of this thesis can be reduced by 14%. A discussion about potential influence of single distribution center on transportation and impact on customers is also included.

Degree

thesis:*
Department dc:contributor.department
Massachusetts Institute of Technology. Department of Mechanical Engineering.
Grantor dc:publisher
Massachusetts Institute of Technology
Year dc:date.issued
2016

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Han, Yan, M. Eng. Massachusetts Institute of Technology
Advisor dc:contributor.advisor
  • Stephen Graves.

Subjects

dc:subject × 1

Rights

dc:rights
Statement dc:rights
  • MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.
Language dc:language.iso
eng

Identifiers

dc:identifier.*
Handle dc:identifier.uri
http://hdl.handle.net/1721.1/106692
OAI identifier oai:identifier
oai:dspace.mit.edu:1721.1/106692

Chain of custody

source
Harvested from
MIT
Base URL
dspace.mit.edu/oai/request
Last updated
2026-07-22
Source record
OAI-PMH GetRecord
citation

Han, Yan, M. Eng. Massachusetts Institute of Technology. Product availability improvement for an analytical consumables supply chain : distribution and transportation. Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106692